Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, Washington, DC 20375, USA.
Sensors (Basel). 2010;10(3):2315-31. doi: 10.3390/s100302315. Epub 2010 Mar 19.
Porphyrins are a family of highly conjugated molecules that strongly absorb visible light and fluoresce intensely. These molecules are sensitive to changes in their immediate environment and have been widely described for optical detection applications. Surfactant-templated organosilicate materials have been described for the semi-selective adsorption of small molecule contaminants. These structures offer high surface areas and large pore volumes within an organized framework. The organic bridging groups in the materials can be altered to provide varied binding characteristics. This effort seeks to utilize the tunable binding selectivity, high surface area, and low materials density of these highly ordered pore networks and to combine them with the unique spectrophotometric properties of porphyrins. In the porphyrin-embedded materials (PEMs), the organosilicate scaffold stabilizes the porphyrin and facilitates optimal orientation of porphyrin and target. The materials can be stored under ambient conditions and offer exceptional shelf-life. Here, we report on the design of PEMs with specificity for organophosphates and compounds of similar structure.
卟啉是一类高度共轭的分子，它们强烈吸收可见光并强烈荧光。这些分子对其周围环境的变化很敏感，已广泛用于光学检测应用。表面活性剂模板的有机硅材料已被描述用于小分子污染物的半选择性吸附。这些结构在有序的框架内提供了高的比表面积和大的孔体积。材料中的有机桥连基团可以改变，以提供不同的结合特性。这项工作旨在利用这些高度有序的孔网络的可调结合选择性、高的比表面积和低的材料密度，并将其与卟啉的独特分光光度性质结合起来。在卟啉嵌入材料（PEM）中，有机硅骨架稳定卟啉并促进卟啉和靶标的最佳取向。该材料可以在环境条件下储存，并具有出色的保质期。在这里，我们报告了对具有有机磷和类似结构化合物特异性的 PEM 的设计。
