Li Min, Li Feng-hua, Du Jing, Wang Zhi-qian, Zheng Ju-fen, Li Zheng, Ping Ping
Department of Ultrasound, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China.
Zhonghua Nan Ke Xue. 2012 Jan;18(1):35-8.
To evaluate the quantitative analysis by real-time elastosonography in the differential diagnosis of obstructive azoospermia (OA) and non-obstructive azoospermia (NOA).
We evaluated the elastosonographic images of 200 cases of OA, 300 cases of NOA and 100 normal healthy controls, calculated the strain ratio of the testis to the scrotal skin and the median strain ratio among the three groups, and analyzed the best cut-off point for differentiating OA and NOA by the receiver operation characteristic (ROC) curve.
The median strain ratio of NOA was 0.49 +/- 0.43, while that of OA was 0.35 +/- 0.31, with significant difference between the two groups (Z = - 19.173, P = 0.000 < 0.017). According to the results of ROC curve analysis, the area under the curve was 0.857 +/- 0.012 and the best cut-off point for differentiating OA and NOA was 0.395 (sensitivity = 84.5%, specificity = 74.5%, accuracy = 80.5%).
Quantitative analysis by real-time elastosonography is a new valuable technique for the differential diagnosis of azoospermia.
评估实时弹性超声成像定量分析在梗阻性无精子症（OA）和非梗阻性无精子症（NOA）鉴别诊断中的应用。
我们评估了200例OA患者、300例NOA患者及100名正常健康对照者的弹性超声图像，计算睾丸与阴囊皮肤的应变比以及三组的中位应变比，并通过受试者操作特征（ROC）曲线分析鉴别OA和NOA的最佳截断点。
NOA的中位应变比为0.49±0.43，而OA为0.35±0.31，两组间差异有统计学意义（Z = - 19.173，P = 0.000 < 0.017）。根据ROC曲线分析结果，曲线下面积为0.857±0.012，鉴别OA和NOA的最佳截断点为0.395（敏感性 = 84.5%，特异性 = 74.5%，准确性 = 80.5%）。
实时弹性超声成像定量分析是无精子症鉴别诊断中有价值的新技术。
