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L.提取物的化学成分、抗氧化及抗菌活性

Chemical Composition, Antioxidant and Antimicrobial Activities of L. Extracts.

作者信息

Gawron-Gzella Anna, Witkowska-Banaszczak Ewa, Bylka Wiesława, Dudek-Makuch Marlena, Odwrot Agnieszka, Skrodzka Natalia

机构信息

Department of Pharmacognosy, University of Medical Sciences in Poznan, 4 OEiêcickiego Street, 60-781 Poznan, Poland.

出版信息

Pharm Chem J. 2016;50(4):244-249. doi: 10.1007/s11094-016-1431-0. Epub 2016 Aug 11.

Abstract

has been used internally for the treatment of intestinal infections and duodenal ulcers, as well as hemorrhoids, phlebitis and varicose veins and female disorders, and topically to heal wounds, burns, and ulcers. In our study, the antioxidant and antimicrobial activities, as well as quantitative analysis of polyphenols (phenolic acids, flavonoids and total polyphenols) in methanol and aqueous extracts from herbs are presented. A correlation between the antioxidant activity and composition of tested extracts indicates that flavonoids are the major compounds causing scavenging of free radicals. Higher content of flavonoids was found in the methanol extract, while the content of total phenolics was higher in the aqueous extract. Both extracts from herbs showed antioxidant activity and high antimicrobial activity in a wide spectrum of test strains.

摘要

它已被用于内部治疗肠道感染、十二指肠溃疡,以及痔疮、静脉炎和静脉曲张和女性疾病,还可局部用于愈合伤口、烧伤和溃疡。在我们的研究中,展示了来自草药的甲醇提取物和水提取物中的抗氧化和抗菌活性,以及多酚(酚酸、黄酮类化合物和总多酚)的定量分析。测试提取物的抗氧化活性与成分之间的相关性表明,黄酮类化合物是导致自由基清除的主要化合物。在甲醇提取物中发现黄酮类化合物的含量较高,而水提取物中总酚类的含量较高。两种草药提取物在广泛的测试菌株中均表现出抗氧化活性和高抗菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea17/7089018/7b2c1467c8d4/11094_2016_1431_Fig1_HTML.jpg

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