Bastiaens Guido J H, Bijker Else M, Sauerwein Robert W
UMC St Radboud, afd. Medische Microbiologie, Nijmegen, the Netherlands.
Ned Tijdschr Geneeskd. 2012;156(5):A4095.
The new global strategy to achieve long-term malaria eradication is based on rapid treatment of individual malaria patients and blocking the spread of Plasmodium parasites in the population. In a number of countries increased funding combined with more effective control measures have resulted in a substantial decline in the incidence of malaria and in the resulting morbidity and mortality. Increasing resistance of Anopheles mosquitoes to insecticides (pyrethroids and DDT), and reduced sensitivity of Plasmodium parasites to various antimalarials increase the need for the development of new vector control strategies and medicines. Vaccine development efforts have been speeding up and a first vaccine is expected within three years.
实现长期消除疟疾的新全球战略基于对个体疟疾病人的快速治疗以及阻断疟原虫在人群中的传播。在一些国家，资金增加与更有效的控制措施相结合，已使疟疾发病率以及由此导致的发病率和死亡率大幅下降。按蚊对杀虫剂（拟除虫菊酯和滴滴涕）的抗药性不断增强，疟原虫对各种抗疟药的敏感性降低，这增加了开发新的病媒控制策略和药物的必要性。疫苗研发工作一直在加速推进，预计三年内将推出首款疫苗。
