University Department of Psychiatry and MRC Unit of Clinical Pharmacology, Littlemore Hospital, Oxford OX4 4XN, UK.
J Psychopharmacol. 1994 Jan;8(1):8-13. doi: 10.1177/026988119400800102.
Twelve healthy female subjects received the following three drinks in a double-blind, semi-balanced, cross over design: (a) 50 g of amino acids without L-tryptophan (LTP); (b) 50 g of amino acid with LTP (balanced); (c) plain water. Compared to both the balanced amino acid mixture and plain water, the LTP drink significantly lowered plasma total and free tryptophan at 4.5 h. However, compared to the two control conditions, there was no effect of the LTP drink on subjective ratings of mood or hunger. Similarly, the LTP drink did not alter significantly either total calorie intake or the macronutrient content of a test meal 5 h after drink ingestion.
十二名健康女性受试者以双盲、半平衡、交叉设计的方式接受了以下三种饮料：（a）不含 L-色氨酸（LTP）的 50 克氨基酸；（b）含有 LTP 的 50 克氨基酸（平衡）；（c）白开水。与平衡氨基酸混合物和白开水相比，LTP 饮料在 4.5 小时显著降低了血浆总色氨酸和游离色氨酸。然而，与两种对照条件相比，LTP 饮料对情绪或饥饿的主观评价没有影响。同样，LTP 饮料也没有显著改变饮料摄入后 5 小时的总热量摄入或测试餐的宏量营养素含量。
