Roberts D C, Huff M W, Carroll K K
Lipids. 1979 Jun;14(6):566-71. doi: 10.1007/BF02533533.
The distribution and composition of the plasma lipoproteins were studied in suckling rabbits and in rabbits either weaned to or fed as young adults cholesterol-free, semipurified diets containing protein of animal (casein) or plant (soy protein isolate) origin. The raised cholesterol levels of the suckling period resulted in an increase of very low density and intermediate density lipoproteins in a making similar to that seen in adult rabbits fed a high fat diet supplemented with cholesterol. Young rabbits fed the cholesterol-free, semipurified, diet containing casein also became hypercholesterolemic but, in this case, the increased cholesterol was found primarily in lipoproteins of intermediate density. Cholesterol levels remained low in those rabbits fed the soy protein isolate diet, and the lipoprotein distribution was somewhat similar to that of chow-fed animals. It appears that the raised cholesterol levels during the suckling period result in different lipoprotein patterns to those produced in young adult animals by a cholesterol-free, semipurified diet.
对哺乳兔以及断奶后或成年后食用不含胆固醇的半纯化日粮（日粮中含有动物来源蛋白质（酪蛋白）或植物来源蛋白质（大豆分离蛋白））的兔的血浆脂蛋白分布和组成进行了研究。哺乳期胆固醇水平升高导致极低密度脂蛋白和中间密度脂蛋白增加，其模式类似于成年兔喂食添加胆固醇的高脂肪日粮时所观察到的情况。喂食不含胆固醇的半纯化酪蛋白日粮的幼兔也出现了高胆固醇血症，但在这种情况下，胆固醇增加主要见于中间密度脂蛋白。喂食大豆分离蛋白日粮的兔胆固醇水平仍较低，且脂蛋白分布与喂食普通饲料动物的脂蛋白分布有些相似。哺乳期胆固醇水平升高似乎导致了与成年幼兔食用不含胆固醇的半纯化日粮所产生的脂蛋白模式不同。
