Zuckerman M J, Ho H, Hooper L, Anderson B, Polly S M
Department of Medicine, Texas Tech University Health Sciences Center, El Paso 79905.
J Clin Gastroenterol. 1990 Oct;12(5):525-32. doi: 10.1097/00004836-199010000-00008.
We examined the frequency of isolation of Blastocystis hominis from stools of patients seen in an indigent-care teaching hospital. Over a 2-year period, 2,744 stool specimens were examined prospectively. B. hominis was found in 262 stools (9.5% of all stool specimens and 53.5% of the positive specimens). Clinical data were obtained from 80 patients with stools positive for B. hominis. B. hominis was the only parasite isolated in 39 of 47 (83%) of the adults, compared with 17 of 33 (52%) of the children (p = 0.006). All but 2 of 52 patients without concomitant parasitic infection or bacterial pathogens in stool had gastrointestinal symptoms (41 abdominal pain, 26 diarrhea, and 5 vomiting), but no association was seen with fever, peripheral leukocytosis, stool occult blood, fecal leukocytes, or endoscopic or radiologic evidence of colitis. Therefore, B. hominis was frequently recovered from stools examined in a hospital clinical parasitology laboratory. The clinical presentations of patients in our series did not suggest that B. hominis was invasive. Most patients with B. hominis probably do not require treatment since they will either have spontaneous resolution of symptoms or will be found to have an alternative explanation for their problem.
我们检查了一家贫困护理教学医院中患者粪便中分离出的人芽囊原虫的频率。在两年时间里，前瞻性地检查了2744份粪便标本。在262份粪便中发现了人芽囊原虫（占所有粪便标本的9.5%，阳性标本的53.5%）。从80例粪便中人芽囊原虫呈阳性的患者那里获得了临床数据。在47名成人中的39名（83%）中，人芽囊原虫是唯一分离出的寄生虫，而在33名儿童中的17名（52%）中也是如此（p = 0.006）。52例粪便中无合并寄生虫感染或细菌病原体的患者中，除2例之外均有胃肠道症状（41例腹痛、26例腹泻和5例呕吐），但未发现与发热、外周血白细胞增多、粪便潜血、粪便白细胞或结肠炎的内镜或放射学证据有关。因此，人芽囊原虫经常在医院临床寄生虫学实验室检查的粪便中被检出。我们系列研究中的患者临床表现并未提示人芽囊原虫具有侵袭性。大多数人芽囊原虫感染患者可能不需要治疗，因为他们要么症状会自行缓解，要么会发现其问题有其他原因。
