Qadri S M, al-Okaili G A, al-Dayel F
Department of Pathology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
J Clin Microbiol. 1989 Nov;27(11):2407-9. doi: 10.1128/jcm.27.11.2407-2409.1989.
A total of 19,252 stool specimens from 12,136 patients were examined by direct microscopy and the ethyl acetate-Formalin concentration method during the last 2 years. All liquid specimens and those in which parasite identification was difficult or equivocal were also examined in trichrome-stained preparations. A total of 3,070 intestinal parasites were seen in 2,889 patients. Blastocystis hominis was found in fecal material from 647 patients (17.5%). A total of 132 cases (25.6%) were observed to be in association with other enteric pathogens. B. hominis in large numbers was present as the only parasite or with other commensals in 515 specimens from patients (79.6%). Of these patients, 239 (46.4%) had symptoms, the most common being abdominal pain (87.9%), constipation (32.2%), diarrhea (23.4%), alternating diarrhea and constipation (14.5%), vomiting (12.5%), and fatigue (10.5%). Forty-three (18%) of the patients were treated with metronidazole (0.5 to 1.0 g/day) because of recurrent symptoms and the presence of large numbers of B. hominis cells in repeated stool specimens. After 7 to 10 days of treatment, all patients became asymptomatic with negative stools on follow-up examinations for B. hominis.
在过去两年中，对来自12136名患者的19252份粪便标本进行了直接显微镜检查和乙酸乙酯-福尔马林浓缩法检查。所有液体标本以及那些寄生虫鉴定困难或不明确的标本也进行了三色染色制片检查。在2889名患者中总共发现了3070种肠道寄生虫。在647名患者（17.5%）的粪便中发现了人芽囊原虫。总共观察到132例（25.6%）与其他肠道病原体有关。大量人芽囊原虫作为唯一的寄生虫或与其他共生菌一起存在于515例患者的标本中（79.6%）。在这些患者中，239例（46.4%）有症状，最常见的是腹痛（87.9%）、便秘（32.2%）、腹泻（23.4%）、腹泻与便秘交替出现（14.5%）、呕吐（12.5%）和疲劳（10.5%）。43例（18%）患者因症状反复且多次粪便标本中存在大量人芽囊原虫细胞而接受甲硝唑治疗（0.5至1.0克/天）。治疗7至10天后，所有患者在人芽囊原虫随访检查时均无症状且粪便检测呈阴性。
