Wilkie W S, Schwieterman Philip
University of Kentucky HealthCare, 800 Rose St, H110, Lexington, KY 40536-0293, USA.
Orthopedics. 2012 Feb;35(2):125-30. doi: 10.3928/01477447-20120123-36.
Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease that, untreated, can lead to permanent joint damage, decrease in quality of life, and disability. Health care professionals play a vital role in caring for patients with rheumatoid arthritis. The therapeutic possibilities in the management of rheumatoid arthritis have changed, with newer biologic therapies that target the inflammatory cascade seen in rheumatoid arthritis. As new treatments become increasingly available, it is important for health care professionals to stay informed. This article provides physicians with a review of biologic therapies currently used for the treatment of rheumatoid arthritis and describe how those therapies are used to manage rheumatoid arthritis.
类风湿性关节炎是一种慢性全身性炎症性自身免疫性疾病,若不治疗,可导致永久性关节损伤、生活质量下降及残疾。医疗保健专业人员在类风湿性关节炎患者的护理中发挥着至关重要的作用。类风湿性关节炎管理中的治疗可能性已经发生了变化,出现了针对类风湿性关节炎中炎症级联反应的新型生物疗法。随着越来越多的新疗法问世,医疗保健专业人员了解最新情况非常重要。本文为医生提供了目前用于治疗类风湿性关节炎的生物疗法综述,并描述了这些疗法如何用于管理类风湿性关节炎。