[激酶抑制剂的最新进展] - Suppr

[Update on kinase inhibitors].

作者信息

Alten R

机构信息

Abteilung Innere Medizin II, Rheumatologie, Schlosspark-Klinik, Lehrkrankenhaus der Charité - Universitätsmedizin Berlin, Heubnerweg 2, 14059, Berlin, Deutschland.

出版信息

Z Rheumatol. 2016 Aug;75(6):611-5. doi: 10.1007/s00393-016-0113-3.

DOI:10.1007/s00393-016-0113-3

PMID:27365023

Abstract

摘要

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本文引用的文献

Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases.

Nat Rev Rheumatol. 2016 Jan;12(1):25-36. doi: 10.1038/nrrheum.2015.167. Epub 2015 Dec 3.

VX-509 (Decernotinib), an Oral Selective JAK-3 Inhibitor, in Combination With Methotrexate in Patients With Rheumatoid Arthritis.

Arthritis Rheumatol. 2016 Jan;68(1):46-55. doi: 10.1002/art.39473.

The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis.

Ann Rheum Dis. 2016 Apr;75(4):687-95. doi: 10.1136/annrheumdis-2014-207191. Epub 2015 Mar 20.

The JAK-STAT pathway: impact on human disease and therapeutic intervention.

Annu Rev Med. 2015;66:311-28. doi: 10.1146/annurev-med-051113-024537.

A randomized, double-blind, placebo-controlled, twelve-week, dose-ranging study of decernotinib, an oral selective JAK-3 inhibitor, as monotherapy in patients with active rheumatoid arthritis.

Arthritis Rheumatol. 2015 Feb;67(2):334-43. doi: 10.1002/art.38949.

Safety and efficacy of tofacitinib, an oral janus kinase inhibitor, for the treatment of rheumatoid arthritis in open-label, longterm extension studies.

J Rheumatol. 2014 May;41(5):837-52. doi: 10.3899/jrheum.130683. Epub 2014 Apr 1.

Tofacitinib: a review of its use in adult patients with rheumatoid arthritis.

Drugs. 2013 Jun;73(8):857-74. doi: 10.1007/s40265-013-0065-8.

Back to the future: oral targeted therapy for RA and other autoimmune diseases.

Nat Rev Rheumatol. 2013 Mar;9(3):173-82. doi: 10.1038/nrrheum.2013.7. Epub 2013 Feb 19.

Tofacitinib or adalimumab versus placebo in rheumatoid arthritis.

N Engl J Med. 2012 Aug 9;367(6):508-19. doi: 10.1056/NEJMoa1112072.

Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis.

N Engl J Med. 2012 Aug 9;367(6):495-507. doi: 10.1056/NEJMoa1109071.

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相似文献

[Update on kinase inhibitors].

Z Rheumatol. 2016 Aug;75(6):611-5. doi: 10.1007/s00393-016-0113-3.

[Glucocorticoids].

Z Rheumatol. 2016 Aug;75(6):591-4. doi: 10.1007/s00393-016-0115-1.

[Methotrexate].

Z Rheumatol. 2016 Aug;75(6):599-603. doi: 10.1007/s00393-016-0118-y.

[Biologics].

Z Rheumatol. 2016 Aug;75(6):604-10. doi: 10.1007/s00393-016-0122-2.

[Intracellular targets : current data on effectiveness and safety profile].

Z Rheumatol. 2013 Nov;72(9):867-72. doi: 10.1007/s00393-013-1139-4.

[Recent progress in the medical treatment of rheumatoid arthritis].

Nihon Yakurigaku Zasshi. 2007 Mar;129(3):182-5. doi: 10.1254/fpj.129.182.

[Coxibs].

Z Rheumatol. 2016 Aug;75(6):595-8. doi: 10.1007/s00393-016-0148-5.

[Rheumatoid arthritis].

Z Rheumatol. 2017 Feb;76(1):8-14. doi: 10.1007/s00393-016-0251-7.

Dose optimization of infliximab in patients with rheumatoid arthritis.

Int J Rheum Dis. 2014 Jan;17(1):5-18. doi: 10.1111/1756-185X.12202. Epub 2013 Nov 1.

Infliximab-associated pneumonitis in rheumatoid arthritis.

J Rheumatol. 2006 Sep;33(9):1917-8.

本文引用的文献

Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases.

Nat Rev Rheumatol. 2016 Jan;12(1):25-36. doi: 10.1038/nrrheum.2015.167. Epub 2015 Dec 3.

VX-509 (Decernotinib), an Oral Selective JAK-3 Inhibitor, in Combination With Methotrexate in Patients With Rheumatoid Arthritis.

Arthritis Rheumatol. 2016 Jan;68(1):46-55. doi: 10.1002/art.39473.

The effect of tofacitinib on pneumococcal and influenza vaccine responses in rheumatoid arthritis.

Ann Rheum Dis. 2016 Apr;75(4):687-95. doi: 10.1136/annrheumdis-2014-207191. Epub 2015 Mar 20.

The JAK-STAT pathway: impact on human disease and therapeutic intervention.

Annu Rev Med. 2015;66:311-28. doi: 10.1146/annurev-med-051113-024537.

A randomized, double-blind, placebo-controlled, twelve-week, dose-ranging study of decernotinib, an oral selective JAK-3 inhibitor, as monotherapy in patients with active rheumatoid arthritis.

Arthritis Rheumatol. 2015 Feb;67(2):334-43. doi: 10.1002/art.38949.

Safety and efficacy of tofacitinib, an oral janus kinase inhibitor, for the treatment of rheumatoid arthritis in open-label, longterm extension studies.

J Rheumatol. 2014 May;41(5):837-52. doi: 10.3899/jrheum.130683. Epub 2014 Apr 1.

Tofacitinib: a review of its use in adult patients with rheumatoid arthritis.

Drugs. 2013 Jun;73(8):857-74. doi: 10.1007/s40265-013-0065-8.

Back to the future: oral targeted therapy for RA and other autoimmune diseases.

Nat Rev Rheumatol. 2013 Mar;9(3):173-82. doi: 10.1038/nrrheum.2013.7. Epub 2013 Feb 19.

Tofacitinib or adalimumab versus placebo in rheumatoid arthritis.

N Engl J Med. 2012 Aug 9;367(6):508-19. doi: 10.1056/NEJMoa1112072.

Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis.

N Engl J Med. 2012 Aug 9;367(6):495-507. doi: 10.1056/NEJMoa1109071.

[Update on kinase inhibitors].

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[Update on kinase inhibitors].

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