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狭窄冠状动脉节段的三维重建及血流阻抗评估

Three-dimensional reconstruction of stenosed coronary artery segments with assessment of the flow impedance.

作者信息

Hulzbosch A A, Slump C H, Viergever M A

机构信息

Philips Medical Systems, Best, The Netherlands.

出版信息

Int J Card Imaging. 1990;5(2-3):135-43. doi: 10.1007/BF01833982.

DOI:10.1007/BF01833982
PMID:2230291
Abstract

In this paper preliminary results of a study about the diagnostic benefits of 3D visualization and quantitation of stenosed coronary artery segments are presented. As is well known, even biplane angiographic images do not provide enough information for binary reconstruction. Therefore, a priori information about the slice to be reconstructed must be incorporated into the reconstruction algorithm. One approach is to assume a circular cross-section of the coronary artery. Hence, the diameter is estimated from the contours of the vessels in both projections. Another approach is to search for a solution of the reconstruction problem close to the previously reconstructed adjacent slice. In this paper we follow the first method based on contour information. The reconstructed coronary segment is visualized in three dimensions. Based on the obtained geometry of the obstruction the pertinent blood flow impedance is estimated on the basis of fluid dynamic principles. The results of applying the reconstruction algorithms to clinical coronary biplane exposure are presented with an indication of the assessed flow impedance.

摘要

本文展示了一项关于三维可视化和狭窄冠状动脉节段定量诊断益处研究的初步结果。众所周知,即使是双平面血管造影图像也无法为二元重建提供足够信息。因此,关于待重建切片的先验信息必须纳入重建算法。一种方法是假设冠状动脉为圆形横截面。因此,直径是根据两个投影中血管的轮廓估计的。另一种方法是在先前重建的相邻切片附近寻找重建问题的解决方案。在本文中,我们采用基于轮廓信息的第一种方法。重建的冠状动脉节段以三维形式可视化。基于获得的阻塞几何形状,根据流体动力学原理估计相关的血流阻抗。给出了将重建算法应用于临床冠状动脉双平面曝光的结果以及评估的血流阻抗指示。

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引用本文的文献

1
Myocardial perfusion in humans: what can we measure?人类心肌灌注:我们能测量什么?
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Relating coronary perfusion to myocardial function using three-dimensional reconstruction of heart and coronary arteries.利用心脏和冠状动脉的三维重建技术将冠状动脉灌注与心肌功能相关联。
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本文引用的文献

1
Dynamic coronary stenosis.动态冠状动脉狭窄
Am J Cardiol. 1980 Feb;45(2):286-92. doi: 10.1016/0002-9149(80)90647-5.
2
Flow characteristics in models of arterial stenoses. II. Unsteady flow.动脉狭窄模型中的血流特性。II. 非定常流动。
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Flow characteristics in models of arterial stenoses. I. Steady flow.动脉狭窄模型中的血流特性。I. 稳定流。
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On the fluid mechanics of human coronary artery stenosis.关于人类冠状动脉狭窄的流体力学
IEEE Trans Biomed Eng. 1975 Jul;22(4):327-34. doi: 10.1109/tbme.1975.324453.
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Effect of geometry on pressure losses across models of arterial stenoses.几何形状对动脉狭窄模型中压力损失的影响。
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Effect of stenotic dimensions and blood flow on the hemodynamic significance of model coronary arterial stenoses.狭窄尺寸和血流对模型冠状动脉狭窄血流动力学意义的影响。
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