Velciov Silvia, Gluhovschi Gh, Sporea I, Trandafirescu Virginia, Petrica Ligia, Bozdog Gh, Gluhovschi Cristina, Bob F, Gădălean Florica, Buzaş Roxana, Bobu Maria, Voicu L
Nephrology Department, University of Medicine and Pharmacy Timişoara, Romania.
Rom J Intern Med. 2011;49(2):113-20.
The study assesses the presence of asymptomatic urinary anomalies in patients with inflammatory bowel disease. Asymptomatic urinary anomalies are mainly due to glomerular nephritis, they being one of the forms of its manifestation, together with chronic nephrotic and nephritic syndromes. We identified urinary anomalies in 18 patients (20%) with bowel inflammatory disease that consisted of haematuria in 8 (9%) patients, isolated proteinuria in 5 (6%) patients and haematuria associated with proteinuria in 5 (6%) patients. Asymptomatic urinary anomalies were more frequent in patients with the Crohn disease than in those with ulcerative colitis. We identified RFG under 60ml/min in 4 patients with asymptomatic urinary anomalies. It is very easy to evaluate asymptomatic urinary anomalies with dipstick. This method is also required in current practice for patients with urinary anomalies for identifying the glomerular disease that might have caused them. One must take into consideration differential diagnosis with other diseases that can manifest themselves with proteinuria or isolated proteinuria. One must also take into account the fact that urinary anomalies may also be related to administration of 5-aminosalicylates.
该研究评估了炎症性肠病患者中无症状性泌尿系统异常的存在情况。无症状性泌尿系统异常主要归因于肾小球肾炎，它是肾小球肾炎的表现形式之一，与慢性肾病综合征和肾炎综合征并存。我们在18例（20%）肠道炎症性疾病患者中发现了泌尿系统异常，其中8例（9%）患者出现血尿，5例（6%）患者出现单纯蛋白尿，5例（6%）患者出现血尿合并蛋白尿。无症状性泌尿系统异常在克罗恩病患者中比在溃疡性结肠炎患者中更常见。我们在4例有无症状性泌尿系统异常的患者中发现肾小球滤过率低于60ml/分钟。使用试纸条评估无症状性泌尿系统异常非常容易。目前在临床上，对于有泌尿系统异常的患者，也需要这种方法来识别可能导致这些异常的肾小球疾病。必须考虑与其他可表现为蛋白尿或单纯蛋白尿的疾病进行鉴别诊断。还必须考虑到泌尿系统异常也可能与5-氨基水杨酸酯的使用有关。
