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血管重建术后的肢体缺血严重程度的功能预后。

Functional outcomes following revascularisation for critical limb ischaemia.

机构信息

Department of Vascular Surgery, Addenbrookes Hospital, Cambridge, UK.

出版信息

Eur J Vasc Endovasc Surg. 2012 Apr;43(4):420-5. doi: 10.1016/j.ejvs.2012.01.015. Epub 2012 Feb 4.

Abstract

OBJECTIVES

More traditional outcome measures following lower limb bypass procedures are poor predictors of functional outcome. This paper aimed to review the effect of infrainguinal bypass surgery on residential and mobility status in patients with critical limb ischaemia.

DESIGN

Review.

METHODS

A Medline search up until April 2011 was undertaken of all studies involving patients with CLI undergoing ILLB and PTA. Studies were reviewed if they addressed the ambulatory/residential status of the patients pre- and post-operatively. Ambulatory status was defined as the ability to walk even with the help of a stick/frames. Independent residential status was defined as living at home with no help.

RESULTS

A total of 10 studies on IILB were deemed suitable for inclusion in the review, reporting 3381 patients (2064 men). Median age ranged from 66 years to 84 years. Thirty day mortality ranged from 0% to 6.3%. Follow-up ranged from 30 days to 1 year. Three studies noted an improvement in ambulation status. No study reported any improvement in residential status after ILLB. Only one study reported on specific improvements in ambulatory status in patients with CLI after PTA.

CONCLUSIONS

ILLB for patients with CLI is not without risk. Patients are not as independent or mobile following surgery. Further studies need to firstly identify the cause(s) of this and to determine optimal methods to return more patients to independence. Furthermore, CLI studies need to routinely report data on functionality.

摘要

目的

下肢旁路手术后的传统评估指标对功能预后的预测效果不佳。本文旨在探讨股腘旁路术对有严重肢体缺血的患者的居住和移动状态的影响。

设计

综述。

方法

对截止 2011 年 4 月的所有涉及接受 ILLB 和 PTA 的 CLI 患者的研究进行了 Medline 检索。如果研究涉及患者术前和术后的活动/居住状态,则对其进行审查。活动状态定义为能够行走,即使借助拐杖/框架。独立居住状态定义为无需帮助即可居家生活。

结果

共有 10 项关于 IILB 的研究被认为适合纳入综述,共纳入 3381 例患者(2064 例男性)。中位年龄从 66 岁到 84 岁不等。30 天死亡率从 0%到 6.3%不等。随访时间从 30 天到 1 年不等。三项研究指出活动状态有所改善。没有研究报告 ILLB 后患者的居住状态有任何改善。只有一项研究报告了 PTA 后 CLI 患者活动状态的具体改善。

结论

对于 CLI 患者,ILLB 并非没有风险。手术后患者的独立性和移动性并未提高。进一步的研究需要首先确定造成这种情况的原因,并确定使更多患者恢复独立性的最佳方法。此外,CLI 研究需要常规报告功能数据。

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