Jepegnanam Thilak S, von Schroeder Herbert P
University of Toronto Hand Program, Toronto Western Hospital, Toronto, Ontario, Canada.
J Hand Surg Am. 2012 Mar;37(3):477-80. doi: 10.1016/j.jhsa.2011.12.020. Epub 2012 Feb 1.
Bone substitutes are being increasingly used and may avert the need for autogenous bone graft in orthopedic surgery. Thus it is important to note complications that occur with them to better understand the limitations. We report on early mechanical failure of injectable calcium sulfate leading to implant failure in 2 elderly patients who had corrective osteotomies for malunited distal radius fractures. We hypothesize that these occurred because there was inadequate new bone formation to replace the resorbing bone substitute. We advise caution when using bone substitutes in patients with expected delayed fracture healing.
骨替代物的使用越来越广泛，在骨科手术中可能避免自体骨移植的需求。因此，了解其出现的并发症对于更好地认识其局限性很重要。我们报告了2例老年患者因桡骨远端骨折畸形愈合行截骨矫形术后，可注射硫酸钙早期出现机械性失效导致植入物失败的情况。我们推测，这些情况的发生是因为新骨形成不足以替代正在吸收的骨替代物。我们建议，对于预期骨折愈合延迟的患者，使用骨替代物时应谨慎。
