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2009 年 H1N1 流感大流行期间孕妇接种 2009-10 年 H1N1 流感疫苗。

2009 H1N1 vaccination by pregnant women during the 2009-10 H1N1 influenza pandemic.

机构信息

Krasnoff Quality Management Institute, North Shore-LIJ Health System, Hempstead, NY, USA.

出版信息

Am J Obstet Gynecol. 2012 Apr;206(4):339.e1-8. doi: 10.1016/j.ajog.2011.12.027. Epub 2011 Dec 30.

DOI:10.1016/j.ajog.2011.12.027
PMID:22306303
Abstract

OBJECTIVE

Pregnant women were identified at greater risk and given priority for 2009 H1N1 vaccination during the 2009 through 2010 H1N1 pandemic. We identified factors associated with acceptance or refusal of 2009 H1N1 vaccination during pregnancy.

STUDY DESIGN

We conducted an in-person survey of postpartum women on the labor and delivery service from June 17 through Aug. 13, 2010, at 4 New York hospitals.

RESULTS

Of 1325 survey respondents, 34.2% received 2009 H1N1 vaccination during pregnancy. A provider recommendation was most strongly associated with vaccine acceptance (odds ratio [OR], 19.4; 95% confidence interval [CI], 12.7-31.1). Also more likely to take vaccine were women indicating the vaccine was safe for the fetus (OR, 12.4; 95% CI, 8.3-19.0) and those who previously took seasonal flu vaccination (OR, 7.9; 95% CI, 5.8-10.7). Race, education, income, and age were less important in accepting vaccine.

CONCLUSION

Greater emphasis on vaccine safety and provider recommendation is needed to increase the number of women vaccinated during pregnancy.

摘要

目的

在 2009 至 2010 年的 H1N1 大流行期间,孕妇被确定为高危人群,并优先接种 2009 年 H1N1 疫苗。我们确定了与孕妇接受或拒绝接种 2009 年 H1N1 疫苗相关的因素。

研究设计

我们在 2010 年 6 月 17 日至 8 月 13 日期间,在纽约的 4 家医院对分娩服务的产后妇女进行了面对面的调查。

结果

在 1325 名调查对象中,34.2%的人在怀孕期间接种了 2009 年 H1N1 疫苗。医生的建议与疫苗接种的接受程度最密切相关(比值比[OR],19.4;95%置信区间[CI],12.7-31.1)。更有可能接种疫苗的是表示疫苗对胎儿安全的妇女(OR,12.4;95%CI,8.3-19.0)和以前接种过季节性流感疫苗的妇女(OR,7.9;95%CI,5.8-10.7)。种族、教育、收入和年龄在接受疫苗方面的作用较小。

结论

需要更加重视疫苗的安全性和医生的建议,以增加怀孕期间接种疫苗的妇女人数。

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