Yiengprugsawan Vasoontara, Banwell Cathy, Seubsman Sam-Ang, Sleigh Adrian C
National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia.
BMJ Open. 2012 Feb 3;2(1):e000561. doi: 10.1136/bmjopen-2011-000561. Print 2012.
To investigate the relationship between short sleep and obesity among Thai adults.
Both 4-year longitudinal and cross-sectional analyses of a large national cohort.
Thai adults residing nationwide from 2005 to 2009.
Cohort members were enrolled as distance learners at Sukhothai Thammathirat Open University (N=87 134 in 2005 and 60 569 at 2009 follow-up). At 2005 baseline, 95% were between 20 and 49 years of age.
Self-reported sleep duration was categorised as <6, 6, 7, 8 and ≥9 h. For all analyses (2005 and 2009 cross-sectional and 2005-2009 longitudinal), we used multinomial logistic regression models to assess the effect of sleep duration on abnormal body size (underweight, overweight-at-risk, obese). Results were adjusted for an array of relevant covariates.
At the last cohort follow-up in 2009, cross-sectional associations linked short sleep (<6 h) and obesity: adjusted ORs (AOR) =1.49, 95% CIs 1.32 to 1.68 for women and AOR=1.36, 95% CI 1.21 to 1.52 for men. The earlier cross-sectional baseline results in 2005 were quite similar. Longitudinal analysis (2005-2009) of 4-year incremental weight gain (5 to <10%, 10 to <20% and 20%+) strongly supported the short sleep-obesity relationship (significant AORs of 1.10, 1.30 and 1.69, respectively).
The results are internally consistent (2005 and 2009) and longitudinally confirmatory of a short sleep effect on obesity among Thai adults. Further research is needed to elucidate causal mechanisms underlying the sleep-obesity relationship.
研究泰国成年人中短睡眠与肥胖之间的关系。
对一个大型全国队列进行4年的纵向和横断面分析。
2005年至2009年居住在泰国全国的成年人。
队列成员作为素可泰·坦玛提腊开放大学的远程学习者入组(2005年有87134人,2009年随访时有60569人)。在2005年基线时,95%的人年龄在20至49岁之间。
自我报告的睡眠时间分为<6小时、6小时、7小时、8小时和≥9小时。对于所有分析(2005年和2009年横断面分析以及2005年至2009年纵向分析),我们使用多项逻辑回归模型来评估睡眠时间对异常体型(体重过轻、超重风险、肥胖)的影响。结果针对一系列相关协变量进行了调整。
在2009年队列的最后一次随访中,横断面分析表明短睡眠(<6小时)与肥胖有关:女性调整后的比值比(AOR)=1.49,95%置信区间为1.32至1.68;男性AOR=1.36,95%置信区间为1.21至1.52。2005年早期的横断面基线结果非常相似。对4年体重增量(5%至<10%、10%至<20%和20%以上)的纵向分析(2005年至2009年)有力地支持了短睡眠与肥胖的关系(分别有显著的AOR为1.10、1.30和1.69)。
结果在内部是一致的(2005年和2009年),并且纵向证实了短睡眠对泰国成年人肥胖的影响。需要进一步研究以阐明睡眠与肥胖关系背后的因果机制。