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年龄大不一定更明智:母亲年龄与产前酒精使用风险。

Older not wiser: risk of prenatal alcohol use by maternal age.

机构信息

San Francisco State University, Child and Adolescent Development Program, 1600 Holloway Avenue,San Francisco, CA 94132, USA.

出版信息

Matern Child Health J. 2013 Jan;17(1):147-55. doi: 10.1007/s10995-012-0953-7.

DOI:10.1007/s10995-012-0953-7
PMID:22307728
Abstract

High levels of alcohol use among pregnant women have been associated with a spectrum of birth defects. Greater maternal age has been related to an increased risk of drinking during pregnancy. Although the context, process, and outcomes of pregnancy and alcohol use vary by maternal age, no studies have examined predictors of prenatal drinking by age. This study addresses this gap by examining potential risk factors associated with prenatal alcohol use (any versus none) by maternal age (<20, 20-25, 26-34, and 35 years or older). Descriptive and logistic regression analyses were completed on survey data from 9,004 pregnant women from the north central U.S. Descriptive statistics revealed teens in general had a higher level or greater occurrence of risk factors previously identified with prenatal drinking compared to older women, yet women of advanced maternal age (35 years or older) were most likely to drink alcohol during pregnancy. Based on the regression by age, 20-25 year old women had the greatest number of significant risk factors associated with prenatal drinking including being employed, white, unmarried, first birth, smoking prenatally, greater levels of depressed mood, and more experiences related to alcohol abuse. The number and patterns of significant predictors of drinking alcohol while pregnant by age encourage greater investigation of other social, contextual factors that might contribute to the risk of prenatal drinking. This is especially salient for women of advanced maternal age, for whom very few significant predictors emerged.

摘要

孕妇饮酒量过高与一系列出生缺陷有关。产妇年龄越大,怀孕期间饮酒的风险就越高。尽管怀孕和饮酒的背景、过程和结果因产妇年龄而异,但尚无研究探讨按年龄划分的产前饮酒的预测因素。本研究通过检查与产前饮酒(有或无)相关的潜在风险因素,填补了这一空白,这些风险因素与产妇年龄(<20 岁、20-25 岁、26-34 岁和 35 岁或以上)有关。对来自美国中北部的 9004 名孕妇的调查数据进行了描述性和逻辑回归分析。描述性统计数据显示,与年龄较大的女性相比,青少年普遍具有更高水平或更多与产前饮酒相关的风险因素,但高龄产妇(35 岁或以上)在怀孕期间最有可能饮酒。根据按年龄划分的回归,20-25 岁的女性与产前饮酒相关的显著风险因素最多,包括就业、白人、未婚、初产妇、产前吸烟、抑郁情绪程度较高以及与酒精滥用相关的经历更多。按年龄划分的饮酒的显著预测因素的数量和模式鼓励对可能导致产前饮酒风险的其他社会、背景因素进行更深入的研究。对于高龄产妇来说,这一点尤为重要,因为她们只有很少的显著预测因素。

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