Guerin Vincent J, 't Hooft Krista W Visser, L'Eplattenier Henry F, Petite Audrey F
VRCC Veterinary Referrals, 1 Bramston Way, Southfields, Laindon, Essex, SS15 6TP, England.
J Am Vet Med Assoc. 2012 Feb 15;240(4):446-9. doi: 10.2460/javma.240.4.446.
A 12-year-old neutered male Springer Spaniel was referred with a 1-year history of recurring urinary tract infections. Repeated treatment with appropriate antimicrobials selected on the basis of bacterial culture and antimicrobial susceptibility results would result in clinical improvement, but recurrence of clinical signs was observed within days after discontinuation of treatment.
Ultrasound examination revealed a tubular, fluid-filled structure dorsal to the bladder that extended from the midlevel of the bladder to the cranial pole of the prostate. Mineralized foci within a heterogeneous prostatic parenchyma were also noted. Dilation of the right ductus deferens (DD) was observed during exploratory laparotomy.
Both DD were surgically removed, and the prostate was biopsied. The histopathological diagnosis was transitional cell carcinoma involving the right DD and the prostate. The dog was treated with meloxicam (0.1 mg/kg [0.05 mg/lb], p.o., q 24 h) for 9 months after diagnosis before being euthanized.
Because the normal DD is rarely visualized during abdominal ultrasonography in dogs, identification of a tubular, fluid-filled structure dorsal to the bladder may indicate an abnormal DD. Transitional cell carcinoma of the DD should be included in the differential diagnoses of affected patients examined for clinical signs involving the urinary tract.
一只12岁已绝育的雄性史宾格犬因有1年复发性尿路感染病史前来就诊。根据细菌培养和药敏结果选用合适的抗菌药物进行反复治疗可使临床症状改善，但停药后数天内临床症状会复发。
超声检查显示膀胱背侧有一个管状的、充满液体的结构，从膀胱中部延伸至前列腺头极。还注意到前列腺实质不均匀，有矿化灶。在剖腹探查术中观察到右侧输精管扩张。
双侧输精管均手术切除，并对前列腺进行活检。组织病理学诊断为移行细胞癌，累及右侧输精管和前列腺。诊断后，该犬用美洛昔康（0.1毫克/千克[0.05毫克/磅]，口服，每24小时一次）治疗9个月后实施安乐死。
由于在犬腹部超声检查中很少能看到正常的输精管，因此在膀胱背侧发现管状、充满液体的结构可能提示输精管异常。对于因涉及泌尿道的临床症状而接受检查的患病动物，输精管移行细胞癌应列入鉴别诊断。
