Lamb C R, Trower N D, Gregory S P
Queen Mother Hospital for Animals, Department of Small Animal Medicine and Surgery, Royal Veterinary College, North Mymms, Hertfordshire.
J Small Anim Pract. 1996 Sep;37(9):413-6. doi: 10.1111/j.1748-5827.1996.tb02438.x.
Ultrasound-guided catheter biopsy of lesions affecting the lower urinary tract was attempted in 12 dogs with mucosal lesions affecting the bladder (nine) or urethra (three). Histological biopsies were obtained by catheter biopsy in 10 dogs, enabling diagnosis of transitional cell carcinoma in five, papilloma in two, prostatic carcinoma in two and chronic cystitis in one. Cytological samples alone were obtained in two dogs, one of which enabled a diagnosis of transitional cell carcinoma; the other contained evidence of haemorrhage and inflammation, but squamous cell carcinoma was found in a subsequent excisional biopsy. Intravesicular haemorrhage after biopsy was observed ultrasonographically in two dogs. Ultrasound guidance enables accurate determination of biopsy catheter position. The size of biopsies obtained by this method may limit the accuracy of histological diagnosis.
对12只患有影响膀胱（9只）或尿道（3只）的黏膜病变的犬尝试进行超声引导下的下尿路病变导管活检。10只犬通过导管活检获得了组织学活检样本，其中5只诊断为移行细胞癌，2只诊断为乳头状瘤，2只诊断为前列腺癌，1只诊断为慢性膀胱炎。2只犬仅获得了细胞学样本，其中1只诊断为移行细胞癌；另一只含有出血和炎症的证据，但在随后的切除活检中发现为鳞状细胞癌。超声检查发现2只犬活检后膀胱内出血。超声引导能够准确确定活检导管的位置。通过这种方法获得的活检样本大小可能会限制组织学诊断的准确性。
