Department of Urology, Shanghai Cancer Center, Shanghai, China.
Dermatol Surg. 2012 May;38(5):783-90. doi: 10.1111/j.1524-4725.2012.02356.x. Epub 2012 Feb 6.
Basal cell carcinoma (BCC) located on the scrotum is rare.
To analyze clinical and pathologic features, discuss therapeutic strategies, and identify prognostic factors of scrotal BCC in Chinese patients.
Between 2000 and 2010, 10 patients with scrotal BCC were diagnosed and treated at our institution. A review was performed using the clinical records and dermatopathologic slides of these patients.
The median patient age was 70. Skin lesions presented as red nodules and brownish plaques. All patients were treated using wide excision without adjuvant therapy. After an average follow-up of 47 months, eight patients were in good health without any relapse. One patient developed left inguinal lymph node metastasis at 21 months that was successfully treated using bilateral inguinal lymphadenectomy. One patient developed bilateral pulmonary metastasis at 48 months and was palliatively treated with chemotherapy. The clinical and histopathologic risk factors predisposing to metastasis were large primary neoplasms; a long period of misdiagnosis; and infiltrating, morpheaform, spiky, irregular outline pathologic patterns.
BCC of the scrotum is rare. It can metastasize after a long period of initial therapy. Long-term surveillance including a complete metastatic examination is recommended for these patients.
阴囊基底细胞癌（BCC）较为罕见。
分析中国患者阴囊 BCC 的临床和病理特征，探讨治疗策略，并确定其预后因素。
2000 年至 2010 年期间，我院诊治了 10 例阴囊 BCC 患者。回顾性分析这些患者的临床记录和皮肤病理切片。
患者中位年龄为 70 岁。皮损表现为红色结节和褐色斑块。所有患者均采用广泛切除术治疗，未行辅助治疗。平均随访 47 个月后，8 例患者无复发，健康状况良好。1 例患者在 21 个月时出现左侧腹股沟淋巴结转移，经双侧腹股沟淋巴结清扫术成功治疗。1 例患者在 48 个月时出现双侧肺转移，接受化疗姑息治疗。易发生转移的临床和组织病理危险因素包括：较大的原发性肿瘤、较长的误诊时间、浸润性、硬斑病样、棘皮样、不规则轮廓的病理模式。
阴囊 BCC 较为罕见，初始治疗后可发生远处转移。建议对这些患者进行长期随访，包括全面的转移检查。
