Dermatology Unit, Singapore General Hospital, Singapore.
Australas J Dermatol. 2012 Feb;53(1):73-5. doi: 10.1111/j.1440-0960.2011.00791.x. Epub 2011 Jul 12.
Diagnosing tuberculids traditionally requires clinicopathological correlation together with positive tuberculin skin tests (TST) or demonstration of Mycobacterium tuberculosis (MTB) DNA by polymerase chain reaction (PCR). Interferon gamma release assays (IGRA) are new laboratory tests approved for the diagnosis of MTB infection. We describe three patients with tuberculids who had no other clinical feature of tuberculosis (TB) infection and negative PCR of skin biopsies. Their diagnoses were aided by positive IGRA.
诊断结核疹传统上需要临床病理相关性，以及结核菌素皮肤试验（TST）阳性或聚合酶链反应（PCR）检测结核分枝杆菌（MTB）DNA。干扰素γ释放试验（IGRA）是一种新的实验室检测方法，已被批准用于诊断 MTB 感染。我们描述了 3 例结核疹患者，他们没有其他结核病（TB）感染的临床特征，皮肤活检的 PCR 也为阴性。他们的诊断得益于阳性的 IGRA。
