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儿童共患注意缺陷多动障碍和焦虑的治疗:多项基线设计分析。

Treatment of comorbid attention-deficit/hyperactivity disorder and anxiety in children: a multiple baseline design analysis.

机构信息

Department of Psychology, University of Alabama, Tuscaloosa, AL 35487-0348, USA.

出版信息

J Consult Clin Psychol. 2012 Apr;80(2):239-44. doi: 10.1037/a0027123. Epub 2012 Feb 6.

DOI:10.1037/a0027123
PMID:22309474
Abstract

OBJECTIVE

The present study evaluated a 10-week psychosocial treatment designed specifically for children with attention-deficit/hyperactivity disorder (ADHD) and a comorbid anxiety disorder.

METHOD

Using a nonconcurrent multiple baseline design, the authors treated 8 children ages 8-12 with ADHD, combined type, and at least 1 of 3 major anxiety disorders (separation anxiety disorder, generalized anxiety disorder, social phobia). The integrated treatment protocol involved parent management training for ADHD and family-based cognitive-behavioral therapy for anxiety. Pretreatment assessments included semistructured diagnostic interviews and other standardized measures to determine study eligibility. Children were randomized to 1 of 3 baseline control conditions (i.e., 2, 3, or 4 weeks) and subsequently treated in a university-based psychosocial treatment clinic. Weekly assessments of ADHD and anxiety disorder symptoms occurred throughout treatment and comprehensive assessments were obtained at pretreatment, 1-week posttreatment, and 6-months posttreatment.

RESULTS

Single-case results supported greater success in the treatment phase relative to the baseline phase for both ADHD and anxiety symptoms, and ADHD and anxiety symptoms appeared to change concurrently. Pre-post group analyses revealed significant and clinically meaningful improvements in ADHD and anxiety symptoms at 1-week posttreatment, but only anxiety symptoms moved into the subclinical range. At 6-months follow-up, treatment effects were maintained with new movement into the subclinical range for ADHD.

CONCLUSIONS

The present study provides initial data on an integrated treatment protocol for ADHD and anxiety. Further replication and evaluation are needed. Implications of the findings are discussed.

摘要

目的

本研究评估了一种专门针对患有注意力缺陷/多动障碍(ADHD)和共患焦虑障碍的儿童的 10 周心理社会治疗。

方法

研究人员采用非同期多项基线设计,对 8 名 8-12 岁的 ADHD、混合型和至少 3 种主要焦虑障碍(分离焦虑障碍、广泛性焦虑障碍、社交恐惧症)之一的儿童进行治疗。综合治疗方案包括 ADHD 的家长管理培训和基于家庭的认知行为疗法治疗焦虑症。治疗前评估包括半结构化诊断访谈和其他标准化评估,以确定研究的合格性。儿童被随机分配到 3 种基线控制条件之一(即 2、3 或 4 周),然后在大学心理社会治疗诊所进行治疗。在治疗期间,每周评估 ADHD 和焦虑症症状,在治疗前、治疗后 1 周和治疗后 6 个月进行全面评估。

结果

单病例结果支持 ADHD 和焦虑症状在治疗阶段相对于基线阶段取得更大的成功,并且 ADHD 和焦虑症状似乎同时发生变化。治疗前后的组分析显示,ADHD 和焦虑症状在治疗后 1 周时显著改善,且具有临床意义,但只有焦虑症状进入亚临床范围。在 6 个月的随访中,ADHD 的治疗效果得到维持,并且进入亚临床范围。

结论

本研究提供了 ADHD 和焦虑症综合治疗方案的初步数据。需要进一步的复制和评估。讨论了研究结果的意义。

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