Carmona Fabio, Hatanaka Lucas S, Barbieri Marco A, Bettiol Heloisa, Toffano Roseli B D, Monteiro Jacqueline P, Manso Paulo H, Carlotti Ana P C P
Department of Paediatrics, Hospital das Clinicas of the Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Brazil.
Cardiol Young. 2012 Oct;22(5):507-13. doi: 10.1017/S1047951111002009. Epub 2012 Feb 6.
To evaluate the growth of children after repair of Tetralogy of Fallot, as well as the influence of residual lesions and socio-economic status.
A total of 17 children, including 10 boys with a median age of 16 months at surgery, were enrolled in a retrospective cohort, in a tertiary care university hospital. Anthropometric (as z-scores), clinical, nutritional, and social data were collected.
Weight-for-age and weight-for-height z-scores decreased pre-operatively and recovered post-operatively in almost all patients, most markedly weight for age. Weight-for-height z-scores improved, but were still lower than birth values in the long term. Long-term height-for-age z-scores were higher than those at birth, surgery, and 3 months post-operatively. Most patients showed catch-up growth for height for age (70%), weight for age (82%), and weight for height (70%). Post-operative residual lesions (76%) influenced weight-for-age z-scores. Despite the fact that most patients (70%) were from low-income families, energy intake was above the estimated requirement for age and gender in all but one patient. There was no influence of socio-economic status on pre- and post-operative growth. Bone age was delayed and long-term-predicted height was within mid-parental height limits in 16 children (93%).
Children submitted to Tetralogy of Fallot repair had pre-operative acute growth restriction and showed post-operative catch-up growth for weight and height. Acute growth restriction could still be present in the long term.
评估法洛四联症修复术后儿童的生长情况，以及残余病变和社会经济地位的影响。
在一家三级医疗大学医院，对17名儿童进行回顾性队列研究，其中包括10名男孩，手术时的中位年龄为16个月。收集人体测量数据（以z评分表示）、临床、营养和社会数据。
几乎所有患者术前年龄别体重和身高别体重z评分下降，术后恢复，年龄别体重下降最为明显。身高别体重z评分有所改善，但长期仍低于出生时的值。长期年龄别身高z评分高于出生时、手术时及术后3个月时。大多数患者在年龄别身高（70%）、年龄别体重（82%）和身高别体重（70%）方面出现追赶生长。术后残余病变（76%）影响年龄别体重z评分。尽管大多数患者（70%）来自低收入家庭，但除一名患者外，所有患者的能量摄入均高于按年龄和性别估算的需求量。社会经济地位对术前和术后生长均无影响。16名儿童（93%）骨龄延迟，长期预测身高在父母身高中值范围内。
接受法洛四联症修复术的儿童术前有急性生长受限，术后在体重和身高方面出现追赶生长。长期仍可能存在急性生长受限。
