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Kidney transplantation in patients with long-term (more than 15 years) prior dialysis therapy.

作者信息

Kimura T, Ishikawa N, Fujiwara T, Sakuma Y, Nukui A, Yashi M, Yagisawa T

机构信息

Division of Renal Surgery and Transplantation, Department of Urology, Jichi Medical University, Shimotsuke-city, Tochigi, Japan.

出版信息

Transplant Proc. 2012 Jan;44(1):75-6. doi: 10.1016/j.transproceed.2011.11.018.

DOI:10.1016/j.transproceed.2011.11.018
PMID:22310583
Abstract

OBJECTIVE

The number of kidney transplantations (KTx) among patients on long-term hemodialysis (HD) is increasing due to the donor shortage in Japan. We investigated the outcomes of KTx among long-term (more than 15 years) patients on HD.

METHODS

We performed 103 KTx between April 2003 and April 2010 including seven patients (one living and six deceased donor grafts), who had been treated with HD for more than 15 years (group 1) compared with 96 patients (94 living and two deceased donor grafts) treated for less than 15 years (group 2) before KTx. We examined the differences in patient and graft survivals and complication rates between the groups.

RESULTS

Acute rejection episodes (ARE) occurred in 2 (29%) group 1 and 22 (22%) group 2 subjects. Urinary tract infections were diagnosed in 1 (14%) group 1 versus 8 (8%) group 2 cases. The incidence of perioperative complications, such as delayed graft function, cytomegalovirus infection, and surgical complications was higher among group 1. The serum creatinine at 1 year after KTx was the same (1.3 mg/dL). The patient/graft survivals were 100%/100% at 1 and 3 years in group 1 versus 100%/100% at 1 and 99%/98% at 3 years in group 2.

CONCLUSION

The outcomes of KTx among long-term dialysis patients were similar to those in short-term dialysis patients.

摘要

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