Welfare and Health Promotion Division, Department of Chronic Disease Prevention, Diabetes Prevention Unit, National Institute for Health and Welfare (THL), Helsinki, Finland.
Risk Manag Healthc Policy. 2009;2:55-64. doi: 10.2147/RMHP.S5262. Epub 2009 Jul 20.
To describe hospitalizations of a cohort of patients with type 1 diabetes mellitus (T1DM) during 1973-1998 in the main complication groups by sex and T1DM lasting on average 9.5 or 16.5 years.
The population (N = 5166) consisted of all Finnish patients with T1DM diagnosed before the age of 18 years between 1965-1979, derived from the Finnish population-based register of T1DM patients. Data on hospitalizations were obtained from the Finnish Hospital Discharge Register.
In the early stages of T1DM, the majority of the use of hospitalizations was due to the treatment of T1DM without complications. Enormous increases were found for complications when diabetes lasted longer (from 9.5 to 16.5 years). For women, the yearly number of bed-days for renal complications increased 4.8-fold, for peripheral vascular disease 4.3-fold, and for ophthalmic complications 2.5-fold. For men, the corresponding increases were as follows: 5-fold, 6.9-fold, and 2.5-fold. The yearly number of bed-days for nephropathy increased 7-fold. Bed-days for T1DM without complications dropped dramatically. The length of stay in hospitalizations decreased notably, but hospital visits increased when the duration of T1DM increased.
Hospitalizations due to complications substantially increase with aging of T1DM patients. Prevention of T1DM is strongly needed.
描述 1973 年至 1998 年间主要并发症组中 1 型糖尿病(T1DM)患者住院情况,按性别和平均病程 9.5 年或 16.5 年分组。
该人群(N=5166)由 1965 年至 1979 年间在 18 岁前确诊的所有芬兰 T1DM 患者组成,这些患者来源于芬兰基于人群的 T1DM 患者登记处。住院数据来自芬兰住院患者登记处。
在 T1DM 的早期阶段,大多数住院是由于治疗无并发症的 T1DM。当糖尿病病程延长(从 9.5 年延长至 16.5 年)时,并发症的住院需求急剧增加。对于女性,肾病并发症的年住院天数增加了 4.8 倍,周围血管疾病增加了 4.3 倍,眼部并发症增加了 2.5 倍。对于男性,相应的增加分别为 5 倍、6.9 倍和 2.5 倍。肾病的年住院天数增加了 7 倍。无并发症的 T1DM 住院天数急剧下降。住院时间明显缩短,但随着 T1DM 持续时间的增加,住院就诊次数增加。
随着 T1DM 患者年龄的增长,并发症导致的住院治疗显著增加。强烈需要预防 T1DM。