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血管内支架置入术与胸廓外旁路手术治疗症状性锁骨下动脉盗血综合征的对比。

Endovascular stenting vs. extrathoracic surgical bypass for symptomatic subclavian steal syndrome.

机构信息

Department of Vascular Surgery, XuanWu Hospital, and Institute of Vascular Surgery, Capital Medical University, Beijing, China.

出版信息

J Endovasc Ther. 2012 Feb;19(1):44-51. doi: 10.1583/11-3692.1.

Abstract

PURPOSE

To analyze the immediate and long-term outcomes of endovascular stenting vs. extrathoracic surgical bypass for subclavian steal syndrome.

METHODS

From 1989 to 2010, 252 consecutive patients (173 men; mean age 62 years) with vertebrobasilar and upper extremity symptoms of subclavian steal were treated with balloon-expandable stents (n=148) or extrathoracic surgical bypasses (n=104: 71 axilloaxillary and 33 carotid-subclavian) using polytetrafluoroethylene grafts.

RESULTS

The technical success rate was 97.3% in the stent group vs. 99.0% for the bypass group (p=0.605). There was no perioperative mortality or any permanent neurological deficit in either group. The overall perioperative complication rate was 6.1% in the stent group vs. 9.6% in the bypass group (p=0.295). The 10-year target vessel revascularization rate was 46.6% for stenting vs. 5.8% for bypass (p<0.001). The cumulative primary patency rates at 1, 3, 5, and 10 years were 91%, 78%, 67%, and 49% for the stent group vs. 99%, 97%, 95%, and 89% for the bypass group (p<0.001). The cumulative secondary patency rates were 95%, 91%, 86%, and 64%, respectively, for the stent group vs. 99%, 99%, 98%, and 94% for the bypass group (p=0.001). No difference was detected in overall survival curves between the groups (p=0.527).

CONCLUSION

Both endovascular stenting and extrathoracic surgical bypass are safe and effective treatments for subclavian steal syndrome in the short and medium term; however, extrathoracic surgical bypasses are more durable in the long term.

摘要

目的

分析血管内支架置入与胸廓外旁路手术治疗锁骨下盗血综合征的即刻和长期疗效。

方法

1989 年至 2010 年,252 例(男 173 例;平均年龄 62 岁)出现椎基底动脉和上肢症状的锁骨下盗血综合征患者接受了球囊扩张支架(n=148)或胸廓外旁路手术(n=104:71 例腋-腋旁路,33 例颈动脉-锁骨下旁路)治疗,使用聚四氟乙烯移植物。

结果

支架组的技术成功率为 97.3%,旁路组为 99.0%(p=0.605)。两组均无围手术期死亡或任何永久性神经功能缺损。支架组的围手术期总并发症发生率为 6.1%,旁路组为 9.6%(p=0.295)。支架组的 10 年靶血管血运重建率为 46.6%,旁路组为 5.8%(p<0.001)。支架组的 1、3、5 和 10 年的累计一期通畅率分别为 91%、78%、67%和 49%,旁路组分别为 99%、97%、95%和 89%(p<0.001)。支架组的累计二期通畅率分别为 95%、91%、86%和 64%,旁路组分别为 99%、99%、98%和 94%(p=0.001)。两组的总生存率曲线无差异(p=0.527)。

结论

血管内支架置入和胸廓外旁路手术治疗锁骨下盗血综合征在短期和中期均安全有效,但胸廓外旁路手术在长期更持久。

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