Niu Guochen, Yan Ziguang, Zhang Bihui, Yang Min
Interventional Radiology and Vascular Surgery Department, Peking University First Hospital, Beijing, China.
Front Neurol. 2020 Apr 24;11:264. doi: 10.3389/fneur.2020.00264. eCollection 2020.
To review technical details and long-term outcomes of endovascular treatment of chronic total occlusion (CTO) of the subclavian artery. From January 2010 to May 2017, 23 patients (17 male; median age, 65 years) underwent endovascular treatment for CTO of the subclavian artery. All lesions had been diagnosed by duplex scanning or computed tomography angiography before treatment. Sixteen (70.0%) patients had symptoms of vertebrobasilar insufficiency, 6 (26.1%) patients had symptoms of arm ischemia, and 2 (8.7%) patients were asymptomatic. Duplex scanning revealed that 16 patients had grade 3 and 7 patients had grade 2 steal blood flow. After recanalization, lesions were treated by stenting. Patients were followed up at 1, 3, 6, and 12 months after endovascular treatment, and annually thereafter. The overall technical success rate was 91.3% (21/23). The successful recanalization rate of antegrade and retrograde approaches were 68.2% (15/22) and 75.0% (6/8), respectively. The rate of clinical symptom remission was 95.2% (20/21) after treatment. No perioperative death or permanent neurological deficits were observed. One patient had arterial dissection treated by covered stent. The estimate cumulative primary and secondary patency rates at 5 years were 74.6 and 78.8%, respectively. Endovascular treatment is a feasible and safe treatment for CTO lesions of the subclavian artery.
回顾锁骨下动脉慢性完全闭塞(CTO)血管内治疗的技术细节和长期疗效。2010年1月至2017年5月,23例患者(17例男性;中位年龄65岁)接受了锁骨下动脉CTO的血管内治疗。所有病变在治疗前均经双功超声扫描或计算机断层血管造影诊断。16例(70.0%)患者有椎基底动脉供血不足症状,6例(26.1%)患者有手臂缺血症状,2例(8.7%)患者无症状。双功超声扫描显示16例患者有3级盗血,7例患者有2级盗血。再通后,病变采用支架置入治疗。血管内治疗后1、3、6和12个月对患者进行随访,此后每年随访一次。总体技术成功率为91.3%(21/23)。顺行和逆行入路的成功再通率分别为68.2%(15/22)和75.0%(6/8)。治疗后临床症状缓解率为95.2%(20/21)。未观察到围手术期死亡或永久性神经功能缺损。1例患者动脉夹层采用覆膜支架治疗。5年时估计的累积原发和继发通畅率分别为74.6%和78.8%。血管内治疗是锁骨下动脉CTO病变可行且安全的治疗方法。