Hodgson S P, Ormerod L P
Department of Orthopaedics, Royal Infirmary, Blackburn BB2 3LR, UK.
J R Coll Surg Edinb. 1990 Aug;35(4):259-62.
A retrospective review of 70 cases of bone and joint tuberculosis seen between 1978 and 1987 is reported. Forty-nine of the cases were patients of Indian subcontinent ethnic origin. There was a wide range of sites affected. Pain, swelling or sinus formation were the commonest presenting features. Delay in diagnosis from the first hospital visit was significantly longer in the Caucasian population (mean delay; Caucasian 17.6 weeks, Indian subcontinent 2.8 weeks). Drug treatment was used in all cases, combined with biopsy in 21 cases and more radical surgery in 28 cases. The results of treatment were good with low morbidity and mortality, long-term problems have been few, and no relapses have occurred. Nine months of chemotherapy and the joint system of orthopaedic and medical management employed locally are strongly recommended.
报告了对1978年至1987年间所见70例骨与关节结核病例的回顾性研究。其中49例患者来自印度次大陆种族。受累部位广泛。疼痛、肿胀或窦道形成是最常见的临床表现。白种人群从首次就诊到确诊的延迟时间明显更长(平均延迟时间;白种人17.6周,印度次大陆2.8周)。所有病例均采用药物治疗,21例联合活检,28例采用更激进的手术。治疗效果良好,发病率和死亡率低,长期问题较少,且未发生复发。强烈推荐九个月的化疗以及当地采用的骨科和内科联合治疗体系。