Federal University of Piauí, DIE, Brazil.
Comput Biol Med. 2012 Apr;42(4):474-9. doi: 10.1016/j.compbiomed.2011.12.016. Epub 2012 Feb 10.
Analysis of HLA data involves queries on web portals, whose search parameters are data stored in laboratories' databases. In order to automate these queries, one approach is to structure laboratory data into a database and to develop bioinformatic tools to perform the data mapping. In this context, we developed the LabSystem Gen tool that allows users to create a Laboratory Information System, without programming. Additionally we implemented a framework that provides bioinformatic tools, transparent access to public HLA (human leukocyte antigen) information resources. We demonstrated the LabSystemGen system by implementing BMDdb, which is a LIMS that manages data of recipients and donors of organ transplant.
HLA 数据分析涉及对门户网站的查询，其搜索参数是存储在实验室数据库中的数据。为了实现这些查询的自动化，可以采用将实验室数据构建成数据库并开发生物信息学工具来执行数据映射的方法。在这种情况下，我们开发了 LabSystem Gen 工具，它允许用户在无需编程的情况下创建实验室信息系统。此外，我们还实现了一个框架，该框架提供了生物信息学工具，可透明访问公共 HLA（人类白细胞抗原）信息资源。我们通过实现 BMDdb 来演示 LabSystemGen 系统，BMDdb 是一个管理器官移植受者和供者数据的 LIM。
