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硬化性腹膜炎与黄体化成人颗粒细胞瘤相关。

Sclerosing peritonitis associated with a luteinized adult granulosa cell tumor.

机构信息

Department of Histopathology, Birmingham Women's Hospital, City Hospital, Birmingham, UK.

出版信息

Int J Gynecol Pathol. 2012 Mar;31(2):141-4. doi: 10.1097/PGP.0b013e3182307b28.

DOI:10.1097/PGP.0b013e3182307b28
PMID:22317869
Abstract

Sclerosing peritonitis is an uncommon condition that has been reported in patients with luteinized ovarian thecomas, although some pathologists have suggested that the underlying ovarian pathology is not always neoplastic. We now report sclerosing peritonitis in a patient with an uncommon, luteinized variant of an adult granulosa cell tumor. To the best of our knowledge, this association has not been described previously. We suggest that sclerosing peritonitis may result from the release of substances by luteinized ovarian stromal cells, in the context of hyperplasia or neoplasia, which stimulate the proliferation of submesothelial fibroblasts.

摘要

硬化性腹膜炎是一种罕见的疾病,已在黄体化卵巢间质细胞瘤患者中报告过,尽管一些病理学家认为潜在的卵巢病理学并非总是肿瘤性的。我们现在报告了一例罕见的成人颗粒细胞瘤黄体化变异型患者的硬化性腹膜炎。据我们所知,这种关联以前尚未描述过。我们认为,硬化性腹膜炎可能是由于黄体化卵巢基质细胞在增生或肿瘤形成的情况下释放物质,刺激了间皮下成纤维细胞的增殖。

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