Jonigk D, Hoeper M M, Kreipe H, Länger F
Institut für Pathologie, Medizinische Hochschule Hannover (MHH), Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Pathologe. 2012 May;33(3):183-91. doi: 10.1007/s00292-011-1560-x.
In pulmonary hypertension there is a discrepancy between the dramatic but unspecific clinical presentation and the remodeling of mostly only limited segments of the vascular compartment of pulmonary parenchyma. Clinical diagnosis relies for the most part on invasive procedures, such as right heart catheterization. Therefore, morphology can provide a reliable etiopathogenetic classification only in close cooperation with the clinical partner disciplines involved. Moreover, the histopathological approach requires intimate knowledge of the vascular anatomy of the lungs and assessment of the parenchyma to be able to diagnose pulmonary hypertension and differentiate between the various types.
在肺动脉高压中，显著但非特异性的临床表现与肺实质血管腔主要仅有限节段的重塑之间存在差异。临床诊断在很大程度上依赖于侵入性检查，如右心导管检查。因此，形态学只有与相关临床合作学科密切协作，才能提供可靠的病因病理分类。此外，组织病理学方法需要深入了解肺的血管解剖结构并评估实质，以便能够诊断肺动脉高压并区分不同类型。
