Root M, Wang T Y, Hescock H, Parker M, Hudson P, Balducci L
Section of Urology, Bay Pines Veterans Hospital, Florida.
J Urol. 1990 Nov;144(5):1239-41. doi: 10.1016/s0022-5347(17)39705-7.
Burkitt's lymphoma is rare in patients older than 50 years and almost never presents as a testicular tumor. We report 2 cases of primary Burkitt's lymphoma of the testicle in men 68 and 79 years old. In 1 man the extragonadal tumor had a rapid and lasting response to combination chemotherapy. The cases are of interest for the unusual presentation of the disease and for the possibility to control Burkitt's lymphoma in older patients without undue toxicity. The management of testicular lymphoma requires radical orchiectomy and prophylactic irradiation of the contralateral testis. Chemotherapy is indicated for advanced disease and may prevent relapses in patients with early disease. The role of central nervous system prophylaxis is controversial.
伯基特淋巴瘤在50岁以上患者中较为罕见，几乎从不表现为睾丸肿瘤。我们报告了2例分别为68岁和79岁男性的原发性睾丸伯基特淋巴瘤病例。其中1例男性患者的性腺外肿瘤对联合化疗有快速且持久的反应。这些病例因其疾病的不寻常表现以及在老年患者中控制伯基特淋巴瘤而不产生过度毒性的可能性而备受关注。睾丸淋巴瘤的治疗需要根治性睾丸切除术以及对侧睾丸的预防性照射。化疗适用于晚期疾病，并且可能预防早期疾病患者的复发。中枢神经系统预防的作用存在争议。
