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扩大经迷路和经尖扩展I型入路治疗大型前庭神经鞘瘤。

The enlarged translabyrinthine and transapical extension type I approach for large vestibular schwannomas.

作者信息

Jayashankar N, Morwani K P, Sankhla S K, Agrawal R

出版信息

Indian J Otolaryngol Head Neck Surg. 2010 Oct;62(4):360-4. doi: 10.1007/s12070-010-0057-x. Epub 2011 Jan 1.

Abstract

To evaluate the results obtained by performing the enlarged translabyrinthine and transapical extension type I approaches for removal of large vestibular schwannomas and those with anterior extensions. An academic tertiary referral centre at Mumbai, India. Retrospective case review. 35 patients of vestibular schwannomas having size greater than 3 cm in extrameatal diameter with extension anterior to the internal auditory canal who underwent the enlarged translabyrinthine or transapical extension type I approach and with a minimum follow up of 1 year are considered. Other subjects who underwent translabyrinthine approach but did not fulfill the above criteria were excluded. Tumor was removed completely in 34 subjects (97.1%). Anatomic interruption of facial nerve occured in 4 cases (11.4%); 3 subjects underwent end to end anastomosis and 1 subject required a cable graft, these were done during the primary procedure itself. At 1 year follow up 28 subjects (80%) had good facial function (Grade I and II, House Brackmann Grading). Postoperative cerebrospinal fluid leak was encountered in 1 subject (2.9%). 34 subjects (97.1%) had a normal albeit slow gait by the sixth post-operative day. Complete tumor removal with a very low morbidity in our series suggest that the enlarged translabyrinthine and transapical extension type I approach offers excellent control of the neurovascular structures in the cerebellopontine angle as also of the large vestibular schwannoma itself aiding complete removal. It also offers the advantage of management of the interrupted facial nerve at the primary procedure itself since the proximal and distal segments are in the operative field.

摘要

评估采用扩大经迷路和经心尖延伸I型入路切除大型前庭神经鞘瘤及伴有向前延伸的肿瘤所取得的结果。印度孟买的一家学术性三级转诊中心。回顾性病例分析。纳入35例前庭神经鞘瘤患者,其肿瘤外耳道直径大于3 cm且延伸至内听道前方,接受了扩大经迷路或经心尖延伸I型入路手术,且至少随访1年。排除其他接受经迷路入路但不符合上述标准的患者。34例患者(97.1%)肿瘤完全切除。4例患者(11.4%)出现面神经解剖学中断;3例患者接受了端端吻合,1例患者需要电缆移植,这些均在初次手术时完成。随访1年时,28例患者(80%)面部功能良好(House - Brackmann分级I级和II级)。1例患者(2.9%)出现术后脑脊液漏。34例患者(97.1%)在术后第6天步态虽正常但缓慢。在我们的系列研究中,肿瘤完全切除且发病率极低,这表明扩大经迷路和经心尖延伸I型入路能很好地控制桥小脑角的神经血管结构以及大型前庭神经鞘瘤本身,有助于完全切除。由于面神经近端和远端均在手术视野内,该入路还具有在初次手术时处理面神经中断的优势。

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