Lordick Florian
Department of Medicine, Klinikum Braunschweig, Hannover Medical School, Germany.
Acta Gastroenterol Belg. 2011 Dec;74(4):530-5.
Treatment options for oesophago-gastric cancers reach from limited resection to multimodality treatment. An accurate clinical assessment and prognostic information are needed for selecting the most appropriate treatment approach. Positron emission tomography (PET) in combination with computed tomography (CT) in a hybrid imaging modality may ameliorate the staging accuracy and add prognostic information. Experiences from specialised centers indicate that PET also may aid to estimate and predict response to preoperative chemotherapy and chemoradiation. This article recapitulates the value of PET in the staging and multidisciplinary care of oesophago-gastric cancer. At this stage, it remains unclear if the prognosis of patients can be improved by implementing PET in the management of this disease. Prospective multicenter studies should be performed to validate metabolic cut-off values and to proof the benefit of PET-guided treatment decisions.
食管癌和胃癌的治疗方案从有限切除到多模式治疗不等。选择最合适的治疗方法需要准确的临床评估和预后信息。正电子发射断层扫描（PET）与计算机断层扫描（CT）相结合的混合成像模式可能会提高分期准确性并增加预后信息。专业中心的经验表明，PET也可能有助于评估和预测对术前化疗和放化疗的反应。本文概述了PET在食管癌和胃癌分期及多学科治疗中的价值。在现阶段，尚不清楚在这种疾病的管理中采用PET是否能改善患者的预后。应开展前瞻性多中心研究，以验证代谢临界值并证明PET引导治疗决策的益处。
