Hayes Thomas, Smyth Elizabeth, Riddell Angela, Allum William
Department of Gastrointestinal Oncology, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK; Department of Radiology, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK; Department of Surgery, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK.
Department of Gastrointestinal Oncology, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK; Department of Radiology, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK; Department of Surgery, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK.
Hematol Oncol Clin North Am. 2017 Jun;31(3):427-440. doi: 10.1016/j.hoc.2017.02.002.
Gastric and esophageal tumors have a poor prognosis; approximately 15% of patients are alive at 10 years following diagnosis. Surgical resection plus adjunctive chemotherapy or chemoradiotherapy is curative in approximately 50% of patients with operable disease, but is also associated with significant morbidity. Therefore, accurate preoperative staging is required to spare patients unnecessary toxicity and futile surgery. This review evaluates the sensitivity and specificities of the modalities used to stage patients with gastroesophageal cancer. Staging techniques reviewed include CT, PET, MRI, EUS, and laparoscopy. The article concludes with suggestions on appropriate staging tools according to site and stage of disease.
胃癌和食管癌预后较差；诊断后10年约15%的患者存活。手术切除加辅助化疗或放化疗可治愈约50%可手术治疗的患者，但也会带来显著的发病率。因此，需要准确的术前分期，以使患者避免不必要的毒性和无效的手术。本综述评估了用于对胃食管癌患者进行分期的各种方法的敏感性和特异性。所综述的分期技术包括CT、PET、MRI、EUS和腹腔镜检查。文章最后根据疾病部位和分期对合适的分期工具提出了建议。
