Reyes García Rebeca, Jódar Gimeno Esteban, García Martín Antonia, Romero Muñoz Manuel, Gómez Sáez José Manuel, Luque Fernández Inés, Varsavsky Mariela, Guadalix Iglesias Sonsoles, Cano Rodriguez Isidoro, Ballesteros Pomar María Dolores, Vidal Casariego Alfonso, Rozas Moreno Pedro, Cortés Berdonces María, Fernández García Diego, Calleja Canelas Amparo, Palma Moya Mercedes, Martínez Díaz-Guerra Guillermo, Jimenez Moleón José J, Muñoz Torres Manuel
Sección de Endocrinología, Hospital Rafael Méndez, Murcia, España.
Endocrinol Nutr. 2012 Mar;59(3):174-96. doi: 10.1016/j.endonu.2012.01.002. Epub 2012 Feb 8.
To provide practical recommendations for evaluation and treatment of osteoporosis associated to endocrine diseases and nutritional conditions.
Members of the Bone Metabolism Working Group of the Spanish Society of Endocrinology, a methodologist, and a documentalist.
Recommendations were formulated according to the GRADE system (Grading of Recommendations, Assessment, Development, and Evaluation) to describe both the strength of recommendations and the quality of evidence. A systematic search was made in MEDLINE (Pubmed), using the following terms associated to the name of each condition: AND "osteoporosis", "fractures", "bone mineral density", and "treatment". Papers in English with publication date before 18 October 2011 were included. Current evidence for each disease was reviewed by two group members, and doubts related to the review process or development of recommendations were resolved by the methodologist. Finally, recommendations were discussed in a meeting of the Working Group.
The document provides evidence-based practical recommendations for evaluation and management of endocrine and nutritional diseases associated to low bone mass or an increased risk of fracture. For each disease, the associated risk of low bone mass and fragility fractures is given, recommendations for bone mass assessment are provided, and treatment options that have shown to be effective for increasing bone mass and/or to decreasing fragility fractures are listed.
为内分泌疾病和营养状况相关的骨质疏松症的评估和治疗提供实用建议。
西班牙内分泌学会骨代谢工作组成员、一名方法学家和一名文献工作者。
根据GRADE系统（推荐分级、评估、制定和评价）制定建议，以描述建议的强度和证据的质量。在MEDLINE（PubMed）中进行系统检索，使用与每种疾病名称相关的以下术语：以及“骨质疏松症”、“骨折”、“骨密度”和“治疗”。纳入2011年10月18日前发表的英文论文。由两名工作组成员审查每种疾病的现有证据，方法学家解决与审查过程或建议制定相关的疑问。最后，在工作组会议上讨论建议。
本文件为低骨量或骨折风险增加相关的内分泌和营养疾病的评估和管理提供了基于证据的实用建议。对于每种疾病，给出了低骨量和脆性骨折的相关风险，提供了骨量评估建议，并列出了已证明对增加骨量和/或降低脆性骨折有效的治疗选择。
