Department of Oral Medicine, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences, Evin, 1983969411, Tehran, Iran.
Med Oral Patol Oral Cir Bucal. 2012 Sep 1;17(5):e728-32. doi: 10.4317/medoral.17718.
To verify the frequency of oral and facial involvement in diagnosed leprosy patients.
This study was performed on 100 leprosy patients (62 male, 38 female, mean ages 51.86±6.1). After explaining the study design, we studied descriptive information including: patient' s sex, age, job, place of birth, familial history of leprosy, types of disease (lepromatous, borderline and tuberculoid leprosy), ocular and oral lesions, facial involvement and neuropathy. The statistical signification was measured by chi-square test.
A total of 46 (23 lepromatous, 15 borderline, and 8 tuberculoid leprosy) out of 100 patients with leprosy had oral lesions. Statistical analysis did not show any significant difference in frequency of oral lesions between different types of disease. Facial lesions were presented in 57 (39 lepromatous, 10 borderline, and 8 tuberculoid leprosy) patients. There was a statistical significant difference in frequency of facial manifestations between different types of leprosy. It has to be mentioned that, atrophy of nasal spine, facial nerve involvement, ocular lesions and facial deformity were seen in 15%, 17%, 22% and 44% of leprosy patients, respectively.
Examination of leprosy patients should be extended to the oral mucosa because oral mucosa may be a secondary source of M.Leprae transmission and infection.
验证已确诊麻风病患者口腔和面部受累的频率。
本研究纳入了 100 例麻风病患者（62 例男性，38 例女性，平均年龄 51.86±6.1 岁）。在解释研究设计后，我们研究了描述性信息，包括：患者的性别、年龄、职业、出生地、麻风病家族史、疾病类型（瘤型、界限类偏瘤型和界限类偏结核样型麻风）、眼部和口腔病变、面部受累和神经病变。采用卡方检验测量统计学意义。
100 例麻风病患者中，共有 46 例（23 例瘤型、15 例界限类偏瘤型和 8 例界限类偏结核样型麻风）存在口腔病变。统计分析显示，不同疾病类型之间口腔病变的频率无显著差异。57 例（39 例瘤型、10 例界限类偏瘤型和 8 例界限类偏结核样型麻风）患者存在面部病变。不同类型的麻风病之间，面部表现的频率存在统计学显著差异。值得一提的是，鼻棘萎缩、面神经受累、眼部病变和面部畸形分别见于 15%、17%、22%和 44%的麻风病患者。
应将麻风病患者的检查扩展到口腔黏膜，因为口腔黏膜可能是 M.Leprae 传播和感染的次要来源。
