Polyvalent Intensive Care Unit, São Francisco Xavier Hospital, CHLO, Lisboa, Portugal.
Biomarkers. 2012 Mar;17(2):180-5. doi: 10.3109/1354750X.2012.654407. Epub 2012 Feb 11.
Post-intensive care unit (ICU) mortality predictors are unknown.
To assess post-ICU in-hospital mortality predictors.
Analysis of 296 patients discharged alive from a medical-surgical ICU during an 18-month period.
Post-ICU in-hospital mortality was 22.6%. Nonsurvivors had significantly higher Charlson comorbidity score and more often had a tracheostomy. C-reactive protein (CRP) "alert measurement", ≥ 6 mg/dL, independently discriminated survivors from nonsurvivors.
A CRP "alert measurement" or the need for tracheostomy may be used to identify patients with high risk of dying after ICU discharge.
Charlson comorbidity score, CRP and tracheostomy predicted post-ICU in-hospital mortality.
重症监护病房（ICU）后死亡率预测因素尚不清楚。
评估 ICU 后院内死亡率预测因素。
对在 18 个月期间从内科-外科 ICU 出院存活的 296 名患者进行分析。
ICU 后院内死亡率为 22.6%。死亡组患者的 Charlson 合并症评分显著更高，且更常需行气管切开术。C 反应蛋白（CRP）“警报测量值”≥6mg/dL 可独立区分存活组与死亡组患者。
CRP“警报测量值”或行气管切开术的需要，可用于识别 ICU 出院后死亡风险较高的患者。
Charlson 合并症评分、CRP 和气管切开术可预测 ICU 后院内死亡率。
