压力、麻醉剂与膜结构：一项自旋探针研究。
Pressure, anesthetics, and membrane structure: a spin-probe study.
作者信息
Finch E D, Kiesow L A
出版信息
Undersea Biomed Res. 1979 Mar;6(1):41-53.
PMID:223265
Abstract
Fatty acid spin-probe analyses at various depths in the membrane bilayer of intact erythrocytes indicate that compressional effects of pressure and fluidizing effects of lipid-soluble anesthetics are detectable only in hydrated regions of the membrane bilayer. Since current theories of anesthetic action cannot explain these observations, a proposal to do so is outlined.
摘要
对完整红细胞膜双层不同深度进行的脂肪酸自旋探针分析表明，压力的压缩效应和脂溶性麻醉剂的流化效应仅在膜双层的水合区域才能检测到。由于目前的麻醉作用理论无法解释这些观察结果，因此概述了一个这样做的提议。
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