Genetically Engineered Materials Science and Engineering Center, MSE, University of Washington, Seattle, WA 98195, USA.
Biosens Bioelectron. 2012 Mar 15;33(1):304-8. doi: 10.1016/j.bios.2012.01.012. Epub 2012 Jan 24.
The binding affinities of graphite-binding peptides to a graphite surface were electrically characterized using sprayed graphene field effect transistors (SGFETs) fabricated with solution exfoliated graphene. The binding affinities of these peptides were also characterized using atomic force microscopy (AFM) and mechanically exfoliated graphene field effect transistors (GFETs) to confirm the validity of the SGFET platform. Binding constants obtained via GFET and AFM were comparable with those observed using SGFETs. The sprayed graphene film serves as a scalable platform to study biomolecular adsorption to graphitic surfaces.
使用溶液剥离的石墨烯制备的喷涂石墨烯场效应晶体管(SGFET)对石墨表面的石墨结合肽的结合亲和力进行了电特性表征。使用原子力显微镜(AFM)和机械剥离石墨烯场效应晶体管(GFET)对这些肽的结合亲和力进行了表征,以确认 SGFET 平台的有效性。通过 GFET 和 AFM 获得的结合常数与通过 SGFET 观察到的结合常数相当。喷涂石墨烯薄膜是研究生物分子在石墨表面吸附的可扩展平台。