Holst Anders Vedel, Danielsen Patricia L, Juhler Marianne
Department of Neurosurgery, University of Copenhagen, Copenhagen, Denmark.
Acta Neurochir Suppl. 2012;114:267-70. doi: 10.1007/978-3-7091-0956-4_52.
The best surgical treatment of cerebral arachnoid cysts is yet to be established. Treatment options are shunting, endoscopic fenestration or microsurgical fenestration through craniotomy.Data from 69 patients with cerebral arachnoid cysts treated in our institution between 1997 and 2007 were reviewed.Cysts were located infratentorially in 20% (n = 14) and supratentorially in 80% (n = 55); of these 73% (n = 40) were in the middle cranial fossa. Mean cyst size was 61 mm (range 15-100 mm). The most common symptoms were headache (51%), dizziness (26%), cranial nerve dysfunction (23%), seizure (22%), nausea and vomiting (18%), and hemiparesis (13%). Surgery was performed in 83% (n = 57). First-line treatments were microsurgical fenestration (n = 30), endoscopic fenestration (n = 15), and cystoperitoneal/ventriculoperitoneal shunting (n = 11). More than one intervention was needed in 42% (n = 24). A particularly high rate of relapse (73%) was observed after endoscopic fenestration, following which 11 patients were admitted for reoperation. By comparison, only eight patients (28%) managed with microsurgical fenestration and four (36%) in the shunted group needed a second surgical procedure. Mean follow-up was 30 months. In the surgical series 79% (n = 45) had a good outcome.We conclude that the surgical treatment of arachnoid cysts has an overall good outcome. In our institution the best results were obtained with microsurgical decompression through craniotomy.
脑蛛网膜囊肿的最佳手术治疗方法尚未确定。治疗选择包括分流术、内镜开窗术或开颅显微手术开窗术。回顾了1997年至2007年在我院接受治疗的69例脑蛛网膜囊肿患者的数据。囊肿位于幕下的占20%(n = 14),幕上的占80%(n = 55);其中73%(n = 40)位于中颅窝。囊肿平均大小为61 mm(范围15 - 100 mm)。最常见的症状是头痛(51%)、头晕(26%)、颅神经功能障碍(23%)、癫痫发作(22%)、恶心呕吐(18%)和偏瘫(13%)。83%(n = 57)的患者接受了手术。一线治疗方法为显微手术开窗术(n = 30)、内镜开窗术(n = 15)和囊肿 - 腹腔/脑室 - 腹腔分流术(n = 11)。42%(n = 24)的患者需要不止一次干预。内镜开窗术后观察到特别高的复发率(73%),之后有11例患者因再次手术入院。相比之下,显微手术开窗术治疗的患者中只有8例(28%)需要二次手术,分流组中有4例(36%)需要二次手术。平均随访时间为30个月。在手术系列中,79%(n = 45)的患者预后良好。我们得出结论,蛛网膜囊肿的手术治疗总体预后良好。在我院,通过开颅显微手术减压获得了最佳效果。