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中国大陆胃癌腹腔镜手术的推广与发展:初步经验

Spread and development of laparoscopic surgery for gastric tumors in mainland China: initial experiences.

作者信息

Chen Xin-Zu, Li Ying-Ying, Hu Jian-Kun, Yang Kun, Liu Jie, Zhang Bo, Chen Zhi-Xin, Chen Jia-Ping, Zhou Zong-Guang

机构信息

Department of Gastrointestinal Surgery, West China Hospital, China.

出版信息

Hepatogastroenterology. 2012 Mar-Apr;59(114):654-8. doi: 10.5754/hge11902.

DOI:10.5754/hge11902
PMID:22328265
Abstract

BACKGROUND/AIMS: To introduce the initial experience of the laparoscopic surgery for gastric tumors in mainland China.

METHODOLOGY

A key Chinese full-text database was comprehensively searched for eligible reports on laparoscopic gastric surgery from 1991 to 2009. Outcomes of laparoscopic gastrectomy for gastric cancer were extracted for pooling estimate.

RESULTS

In the period 2003-2008, the amount of relevant journal papers sharply increased (p<0.001). Analysis included 67 reports (no randomized controlled trial, 4 case control studies and the remnant of case series or case reports); 74.6% of the reports were from institutions in the Eastern China region. Finally 542 patients of gastric cancer were analyzed. Early gastric cancer (TNM stage Ia/Ib) was only 30.0%. D2/D2+ lymphadenectomy was performed in 69.0% patients. The combined overall complication and mortality rates were 10.9% and 0.4%, respectively. The incidence of conversion to open surgery and reoperation were 4.1% and 1.1%, respectively. The long-term outcome of 5-year survival rate was unavailable.

CONCLUSIONS

Laparoscopic gastric surgery has spread rapidly and developed in mainland China during recent several years. The initial experiences from mainland China showed that postoperative complication and mortality rates of laparoscopic gastrectomy for gastric cancer were acceptable and comparable to Japanese and Korean trials.

摘要

背景/目的:介绍中国大陆腹腔镜胃肿瘤手术的初步经验。

方法

全面检索一个重要的中文全文数据库,以获取1991年至2009年期间关于腹腔镜胃手术的合格报告。提取腹腔镜胃癌切除术的结果进行汇总估计。

结果

在2003 - 2008年期间,相关期刊论文数量急剧增加(p<0.001)。分析纳入67篇报告(无随机对照试验,4篇病例对照研究以及其余的病例系列或病例报告);74.6%的报告来自中国东部地区的机构。最终分析了542例胃癌患者。早期胃癌(TNM分期Ia/Ib)仅占30.0%。69.0%的患者进行了D2/D2 +淋巴结清扫术。总体并发症和死亡率分别为10.9%和0.4%。中转开腹手术和再次手术的发生率分别为4.1%和1.1%。5年生存率的长期结果不可用。

结论

近年来,腹腔镜胃手术在中国大陆迅速传播并发展。中国大陆的初步经验表明,腹腔镜胃癌切除术的术后并发症和死亡率是可以接受的,与日本和韩国的试验结果相当。

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