Namboodiri Vasudevan, George Sanju, Boulay Sylvie, Fair Mandy
Birmingham and Solihull Mental Health NHS Trust, Addiction Psychiatry, The Bridge, 15 Larch Croft, Birmingham B37 7UR, UK.
BMJ Case Rep. 2010;2010. doi: 10.1136/bcr.09.2009.2246. Epub 2010 Feb 11.
Heroin misuse in pregnancy is a significant health and social problem, and it can have an adverse effect on the mother and the baby. Although heroin and methadone have no specific teratogenic potential, 48-94% of children exposed in utero will have neonatal abstinence syndrome (NAS). The primary aim of this case report is to raise awareness of NAS among clinicians and to remind them that although very common, it is not inevitable. The risk of NAS can be further minimised by offering comprehensive and co-ordinated antenatal care that addresses the various biopsychosocial needs of the pregnant woman. Further, a brief description of NAS and a review of evidence in the field of management of opioid misuse in pregnancy, as relevant to this case, are provided. We have also included the patient's own reflections on her pregnancy and treatment.
孕期滥用海洛因是一个严重的健康和社会问题，它会对母亲和婴儿产生不良影响。虽然海洛因和美沙酮没有特定的致畸潜能，但48%至94%在子宫内接触过海洛因的儿童会出现新生儿戒断综合征（NAS）。本病例报告的主要目的是提高临床医生对NAS的认识，并提醒他们，尽管NAS非常常见，但并非不可避免。通过提供全面且协调的产前护理，满足孕妇各种生物心理社会需求，可以进一步降低NAS的风险。此外，还提供了与该病例相关的NAS简要描述以及孕期阿片类药物滥用管理领域的证据综述。我们还纳入了患者对其孕期及治疗的自身思考。
