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本文引用的文献

1
Prescriptions, power and politics: the turbulent history of methadone maintenance in Canada.处方、权力与政治:加拿大美沙酮维持治疗的动荡历史。
J Public Health Policy. 2000;21(2):187-210.
2
Methadone and quality of life.美沙酮与生活质量。
Lancet. 1999 Mar 27;353(9158):1101. doi: 10.1016/S0140-6736(05)76462-X.
3
Methadone programmes. The costs and benefits to society and the individual.美沙酮项目。对社会和个人的成本与收益。
Pharmacoeconomics. 1996 Oct;10(4):321-6. doi: 10.2165/00019053-199610040-00002.
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Role of maintenance treatment in opioid dependence.维持治疗在阿片类物质依赖中的作用。
Lancet. 1999 Jan 16;353(9148):221-6. doi: 10.1016/S0140-6736(98)05356-2.
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Effective medical treatment of opiate addiction. National Consensus Development Panel on Effective Medical Treatment of Opiate Addiction.阿片类成瘾的有效医学治疗。阿片类成瘾有效医学治疗全国共识发展小组。
JAMA. 1998 Dec 9;280(22):1936-43.
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The case for a heroin substitution treatment trial in Canada.在加拿大进行海洛因替代治疗试验的理由。
Can J Public Health. 1997 Nov-Dec;88(6):367-70. doi: 10.1007/BF03403907.
7
High rates of HIV infection among injection drug users participating in needle exchange programs in Montreal: results of a cohort study.参与蒙特利尔针具交换项目的注射吸毒者中艾滋病毒感染率高:一项队列研究的结果
Am J Epidemiol. 1997 Dec 15;146(12):994-1002. doi: 10.1093/oxfordjournals.aje.a009240.
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Needle exchange is not enough: lessons from the Vancouver injecting drug use study.针头交换并不够:温哥华注射吸毒研究的教训
AIDS. 1997 Jul;11(8):F59-65. doi: 10.1097/00002030-199708000-00001.
9
Methadone maintenance treatment: an update.美沙酮维持治疗:最新进展
Eur Arch Psychiatry Clin Neurosci. 1995;245(2):114-24. doi: 10.1007/BF02190738.
10
Six-year follow-up of opioid addicts after admission to treatment.阿片类药物成瘾者入院治疗后的六年随访
Arch Gen Psychiatry. 1982 Nov;39(11):1318-23. doi: 10.1001/archpsyc.1982.04290110070012.

比较接受美沙酮治疗的阿片类药物使用者与未接受治疗的阿片类药物使用者:一项针对多伦多阿片类药物使用者队列的随访研究结果。

Comparing opiate users in methadone treatment with untreated opiate users: results of a follow-up study with a Toronto opiate user cohort.

作者信息

Fischer B, Gliksman L, Rehm J, Daniel N, Medved W

机构信息

Department of Public Health Sciences, University of Toronto, ON.

出版信息

Can J Public Health. 1999 Sep-Oct;90(5):299-303. doi: 10.1007/BF03404513.

DOI:10.1007/BF03404513
PMID:10570570
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6980134/
Abstract

Untreated opiate use is correlated with major social harms and costs in Canada. While methadone treatment has existed in Canada since the 1960s, there is little specific Canadian research on its effects. This paper reports on the one-year follow-up results of a Toronto cohort study of opiate users (N = 114) who were not in treatment at baseline. Sixty-nine people were recruited for re-interviewing. A number of these individuals (N = 29) had entered methadone treatment during the year between baseline and follow-up interviews. Comparisons with respect to social functioning, health status and health care utilization, drug use and related risks, and criminal justice system involvement were made between the follow-up subsample who remained untreated, and the subjects who entered methadone treatment. Differences were found with respect to illegal income generation, illicit opiate and other drug use, illicit drug market activities and emergency care and aspects of socio-economic integration, but no major effects on health and criminal justice status could be shown. Research and policy implications are discussed.

摘要

在加拿大,未经治疗的阿片类药物使用与重大社会危害及成本相关。自20世纪60年代以来,美沙酮治疗就在加拿大存在,但加拿大几乎没有关于其效果的具体研究。本文报告了一项针对多伦多阿片类药物使用者队列研究(N = 114)的一年随访结果,这些使用者在基线时未接受治疗。69人被招募进行再次访谈。其中一些人(N = 29)在基线访谈和随访访谈之间的这一年中进入了美沙酮治疗。对仍未接受治疗的随访子样本与进入美沙酮治疗的受试者在社会功能、健康状况和医疗保健利用、药物使用及相关风险以及刑事司法系统参与方面进行了比较。在非法收入产生、非法阿片类药物和其他药物使用、非法毒品市场活动以及急诊护理和社会经济融合方面发现了差异,但未显示出对健康和刑事司法状况有重大影响。讨论了研究和政策意义。