• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Goec kerman 疗法:一种非常有效的治疗方法,却常被遗忘——用于治疗严重的全身性银屑病。

Goeckerman therapy: a very effective, yet often forgotten treatment for severe generalized psoriasis.

机构信息

University of Arizona, College of Medicine, Tucson, AZ, USA.

出版信息

J Dermatolog Treat. 2013 Feb;24(1):34-7. doi: 10.3109/09546634.2012.658014. Epub 2012 Mar 4.

DOI:10.3109/09546634.2012.658014
PMID:22329632
Abstract

As early as 1925, patients suffering from psoriasis have been effectively treated with combination crude coal tar and ultraviolet B radiation, commonly known as Goeckerman therapy. Even though the efficacy of Goeckerman therapy is as good as, if not better than, other more recently available treatment options, its use virtually disappeared after extended inpatient therapies became no longer feasible in the USA. Our clinic at the University of California San Francisco is one of the few outpatient dermatologic clinics that still offer Goeckerman therapy. We present a case report of a patient with severe generalized plaque-type psoriasis, who demonstrated dramatic improvement within 28 days of Goeckerman therapy. It is our hope that this case report serves to remind physicians that Goeckerman therapy is viable treatment option for patients with severe psoriasis, especially those with treatment-resistant psoriasis.

摘要

早在 1925 年,采用复方粗煤焦油和紫外线 B 辐射(通常称为 Goeckerman 疗法)治疗银屑病患者就取得了显著疗效。尽管 Goeckerman 疗法的疗效与其他最近可用的治疗方法相当,如果不是更好的话,但在美国,长期住院治疗不再可行后,其应用几乎消失了。我们在加州大学旧金山分校的诊所是少数提供 Goeckerman 疗法的门诊皮肤科诊所之一。我们报告了一例患有严重全身性斑块型银屑病的患者,该患者在接受 Goeckerman 治疗后 28 天内病情显著改善。我们希望本病例报告能提醒医生,Goeckerman 疗法是治疗严重银屑病患者的可行选择,尤其是那些对治疗有抵抗的银屑病患者。

相似文献

1
Goeckerman therapy: a very effective, yet often forgotten treatment for severe generalized psoriasis.Goec kerman 疗法:一种非常有效的治疗方法,却常被遗忘——用于治疗严重的全身性银屑病。
J Dermatolog Treat. 2013 Feb;24(1):34-7. doi: 10.3109/09546634.2012.658014. Epub 2012 Mar 4.
2
Goeckerman therapy for the treatment of eczema: a practical guide and review of efficacy.戈奎尔曼疗法治疗湿疹:实用指南和疗效评价。
J Dermatolog Treat. 2013 Feb;24(1):2-6. doi: 10.3109/09546634.2011.607794. Epub 2011 Aug 24.
3
Modern modified 'ultra' Goeckerman therapy: a PASI assessment of a very effective therapy for psoriasis resistant to both prebiologic and biologic therapies.现代改良“超”戈克曼疗法:对一种对益生元疗法和生物疗法均耐药的银屑病非常有效的疗法的银屑病面积和严重程度指数评估
J Dermatolog Treat. 2005 Apr;16(2):102-7. doi: 10.1080/09546630510033140.
4
Narrow band ultraviolet-B versus Goeckerman therapy for psoriasis with and without acitretin: A retrospective study.窄谱中波紫外线与Goeckerman疗法治疗有或无阿维A的银屑病:一项回顾性研究。
Indian J Dermatol Venereol Leprol. 2015 Nov-Dec;81(6):584-7. doi: 10.4103/0378-6323.168329.
5
Efficacy, safety, and cost of Goeckerman therapy compared with biologics in the treatment of moderate to severe psoriasis.与生物制剂相比,Goeckerman疗法治疗中度至重度银屑病的疗效、安全性和成本。
Int J Dermatol. 2009 Jun;48(6):653-8. doi: 10.1111/j.1365-4632.2009.04012.x.
6
Goeckerman regimen for management of psoriasis refractory to biologic therapy: the University of California San Francisco experience.用于治疗对生物疗法难治的银屑病的戈克曼疗法:加利福尼亚大学旧金山分校的经验。
J Am Acad Dermatol. 2013 Oct;69(4):648-9. doi: 10.1016/j.jaad.2010.08.030.
7
The role of tar in Goeckerman therapy.焦油在戈克曼疗法中的作用。
Arch Dermatol. 1982 May;118(5):319-21.
8
Crude Coal Tar and Ultraviolet (UV) A radiation (Modified Goeckerman Technique) in Treatment of Psoriasis.粗煤焦油与紫外线A辐射(改良的戈克曼技术)治疗银屑病
Acta Dermatovenerol Croat. 2015;23(3):165-70.
9
Topical tazarotene vs. coal tar in stable plaque psoriasis.局部他扎罗汀与煤焦油治疗稳定斑块状银屑病的疗效比较。
Clin Exp Dermatol. 2010 Jul;35(5):482-6. doi: 10.1111/j.1365-2230.2009.03610.x. Epub 2009 Oct 23.
10
LCD plus NB-UVB reduces time to improvement of psoriasis vs. NB-UVB alone.与单独使用窄谱中波紫外线(NB-UVB)相比,液晶显示屏(LCD)联合NB-UVB可缩短银屑病改善时间。
J Drugs Dermatol. 2009 Apr;8(4):351-7.

引用本文的文献

1
Personalized medicine-concepts, technologies, and applications in inflammatory skin diseases.个性化医疗——炎症性皮肤病中的概念、技术及应用
APMIS. 2019 May;127(5):386-424. doi: 10.1111/apm.12934.
2
Does imiquimod pretreatment optimize 308-nm excimer laser (UVB) therapy in psoriasis patients?咪喹莫特预处理能否优化银屑病患者的308纳米准分子激光(UVB)治疗?
Photodermatol Photoimmunol Photomed. 2017 Jul;33(4):193-202. doi: 10.1111/phpp.12299. Epub 2017 Apr 20.
3
Selected Inflammatory and Metabolic Markers in Psoriatic Patients Treated with Goeckerman Therapy.
接受Goeckerman疗法治疗的银屑病患者的选定炎症和代谢标志物
Mediators Inflamm. 2015;2015:979526. doi: 10.1155/2015/979526. Epub 2015 Jun 8.
4
Serum level of antibody against benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in people dermally exposed to PAHs.人体经皮暴露于多环芳烃后血清中苯并[a]芘-7,8-二醇-9,10-环氧化物-DNA 加合物的抗体水平。
J Immunol Res. 2014;2014:834389. doi: 10.1155/2014/834389. Epub 2014 Apr 13.