University of Arizona, College of Medicine, Tucson, AZ, USA.
J Dermatolog Treat. 2013 Feb;24(1):34-7. doi: 10.3109/09546634.2012.658014. Epub 2012 Mar 4.
As early as 1925, patients suffering from psoriasis have been effectively treated with combination crude coal tar and ultraviolet B radiation, commonly known as Goeckerman therapy. Even though the efficacy of Goeckerman therapy is as good as, if not better than, other more recently available treatment options, its use virtually disappeared after extended inpatient therapies became no longer feasible in the USA. Our clinic at the University of California San Francisco is one of the few outpatient dermatologic clinics that still offer Goeckerman therapy. We present a case report of a patient with severe generalized plaque-type psoriasis, who demonstrated dramatic improvement within 28 days of Goeckerman therapy. It is our hope that this case report serves to remind physicians that Goeckerman therapy is viable treatment option for patients with severe psoriasis, especially those with treatment-resistant psoriasis.
早在 1925 年,采用复方粗煤焦油和紫外线 B 辐射(通常称为 Goeckerman 疗法)治疗银屑病患者就取得了显著疗效。尽管 Goeckerman 疗法的疗效与其他最近可用的治疗方法相当,如果不是更好的话,但在美国,长期住院治疗不再可行后,其应用几乎消失了。我们在加州大学旧金山分校的诊所是少数提供 Goeckerman 疗法的门诊皮肤科诊所之一。我们报告了一例患有严重全身性斑块型银屑病的患者,该患者在接受 Goeckerman 治疗后 28 天内病情显著改善。我们希望本病例报告能提醒医生,Goeckerman 疗法是治疗严重银屑病患者的可行选择,尤其是那些对治疗有抵抗的银屑病患者。