Danielsen Patricia Louise, Schønning Kristian, Larsen Helle Kiellberg
Dermatologisk Afdeling, Bispebjerg Hospital, 2400 København NV, Denmark.
Ugeskr Laeger. 2012 Feb 13;174(7):425-6.
In this case report we present an otherwise healthy 63 year-old male patient with herpes zoster corresponding to the 2nd left branch of the trigeminal nerve. Real time-polymerase chain reaction analyses were positive for both herpes simplex virus (HSV) type 1 and varicella zoster virus (VZV). The most probable explanation is that this reflects asymptomatic, latent expression of HSV-1 in a herpes zoster patient with no clinical relevance. Another hypothesis is that reactivation of a neurotropic herpes virus can reactivate another neurotropic virus if both types are present in the same ganglion. If co-infection with HSV/VZV is suspected the treatment regimen for herpes zoster will sufficiently treat a possible HSV infection also.
在本病例报告中，我们介绍了一名63岁的男性患者，身体健康，患有与三叉神经左第二分支相对应的带状疱疹。实时聚合酶链反应分析显示单纯疱疹病毒1型（HSV）和水痘带状疱疹病毒（VZV）均呈阳性。最可能的解释是，这反映了HSV-1在带状疱疹患者中的无症状潜伏表达，并无临床相关性。另一种假设是，如果两种嗜神经疱疹病毒同时存在于同一神经节中，一种嗜神经疱疹病毒的再激活可能会激活另一种嗜神经病毒。如果怀疑是HSV/VZV合并感染，带状疱疹的治疗方案也将充分治疗可能的HSV感染。
