School of Dietetics and Human Nutrition, CINE Building Macdonald Campus, McGill University, 21,111 Lakeshore Road, Sainte Anne-de-Bellevue, Montreal, QC, H9X 3V9, Canada.
AIDS Behav. 2012 Nov;16(8):2216-25. doi: 10.1007/s10461-012-0153-x.
HIV infection is linked to increased prevalence of depression which may affect maternal caregiving practices and place infants at increased risk of illness. We examined the incidence and days ill with diarrhea among infants of HIV positive (HIV-P), HIV negative (HIV-N), and unknown HIV status (HIV-U) women, and determined if symptoms of maternal postnatal depression (PND) modulated the risk of diarrhea. Pregnant women (n = 492) were recruited from three antenatal clinics; mothers and infants were followed for 12 months postpartum. Diarrheal incidence was 0.6 episodes/100 days at risk. More HIV-P than HIV-N and HIV-U women tended to report PND symptoms (χ(2) = 4.76; P = 0.09). Reporting symptoms was associated with an increased risk of infantile diarrhea only among HIV-P and HIV-U but not HIV-N women (interaction term, χ(2) = 7.84; P = 0.02). Health care providers should be aware of the increased risk of infantile diarrhea when both maternal HIV and PND symptoms are present and take preventive action.
HIV 感染与抑郁的高发率相关，这可能会影响母婴护理行为，并使婴儿患病的风险增加。我们研究了 HIV 阳性（HIV-P）、HIV 阴性（HIV-N）和 HIV 未知状态（HIV-U）女性的婴儿腹泻的发病率和患病天数，并确定了产后抑郁（PND）症状是否会影响腹泻的风险。从三个产前诊所招募了孕妇（n = 492）；对母亲和婴儿进行了 12 个月的产后随访。腹泻的发病率为 0.6 次/100 天。与 HIV-N 和 HIV-U 女性相比，更多的 HIV-P 女性倾向于报告 PND 症状（χ(2) = 4.76；P = 0.09）。仅在 HIV-P 和 HIV-U 女性中，报告症状与婴儿腹泻的风险增加相关，而在 HIV-N 女性中则不相关（交互项，χ(2) = 7.84；P = 0.02）。当母婴 HIV 和 PND 症状均存在时，医疗保健提供者应意识到婴儿腹泻的风险增加，并采取预防措施。
