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胸主动脉瘤的血管内治疗:2012年的技术现状

Endovascular therapy for thoracic aortic aneurysms: state of the art in 2012.

作者信息

Brozzi Nicolas A, Roselli Eric E

机构信息

Department of Thoracic and Cardiovascular Surgery, Desk J4-1, Heart and Vascular Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.

出版信息

Curr Treat Options Cardiovasc Med. 2012 Apr;14(2):149-63. doi: 10.1007/s11936-012-0169-6.

Abstract

Conventional surgery for thoracic aortic pathology involves replacing the affected segment of aorta with an interposition graft and often requires the use of extracorporeal circulatory support with or without deep hypothermic circulatory arrest. Although operative results have improved consistently over 60 years, patients with extensive aneurysms face a considerable risk with conventional surgery, particularly when burdened with multiple comorbidities. Thoracic endovascular aortic repair (TEVAR) was first performed in 1994 and has become a well-established alternative therapy for many thoracic aortic pathologies. TEVAR is most frequently performed through a small groin incision to access the common femoral artery. Wires and catheters are used to deliver and deploy the stent graft in the thoracic aorta under fluoroscopic control. Occasionally, TEVAR is performed as part of a complex hybrid procedure including one stage of conventional open surgery that may utilize a thoracic incision and cardiopulmonary bypass support. The less invasive nature of TEVAR offers the potential for lower mortality and peri-procedural morbidity. Although long-term results of TEVAR are still being gathered, mid-term results are excellent and most late vascular complications can be treated with additional transcatheter procedures. Recent development of fenestrated and branched stent grafts is expanding the application of endovascular therapies to complex aortic pathologies involving the thoracoabdominal aorta and aortic arch. Although conventional techniques continue to be the gold standard for treatment of ascending aortic pathology, recent reports have proven TEVAR to be a viable alternative in specific situations. Design improvements continue to expand the indications for TEVAR, and technological advancements in the field of imaging facilitate safer and more accurate planning, delivery, and assessment of patients with thoracic aortic aneurysms. Hybrid operating rooms provide the optimal environment with state of the art imaging technology for the cardiovascular team to perform TEVAR or alternative hybrid procedures.

摘要

胸主动脉疾病的传统手术包括用植入移植物替换主动脉的病变节段,通常需要使用体外循环支持,可伴有或不伴有深低温停循环。尽管手术效果在60多年来持续改善,但患有广泛动脉瘤的患者接受传统手术面临相当大的风险,尤其是伴有多种合并症时。胸主动脉腔内修复术(TEVAR)于1994年首次实施,已成为许多胸主动脉疾病公认的替代治疗方法。TEVAR最常通过腹股沟小切口进入股总动脉来进行。在荧光镜控制下,使用导丝和导管将覆膜支架输送并部署到胸主动脉。偶尔,TEVAR作为复杂杂交手术的一部分进行,包括一期传统开放手术,可能需要胸部切口和体外循环支持。TEVAR的微创性质具有降低死亡率和围手术期发病率的潜力。尽管TEVAR的长期结果仍在收集,但中期结果良好,大多数晚期血管并发症可通过额外的经导管手术治疗。开窗和分支覆膜支架的最新进展正在将血管内治疗的应用扩展到涉及胸腹主动脉和主动脉弓的复杂主动脉疾病。尽管传统技术仍然是治疗升主动脉疾病的金标准,但最近的报告已证明TEVAR在特定情况下是一种可行的替代方法。设计改进不断扩大TEVAR的适应症,成像领域的技术进步有助于更安全、准确地对胸主动脉瘤患者进行手术规划、手术实施和评估。杂交手术室为心血管团队进行TEVAR或其他杂交手术提供了拥有先进成像技术的最佳环境。

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