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分支型主动脉弓部替换术与象鼻手术在杂交技术治疗胸主动脉病变中的应用对比。

Arch debranching versus elephant trunk procedures for hybrid repair of thoracic aortic pathologies.

机构信息

Division of Vascular Surgery and Endovascular Therapy, University of Florida College of Medicine, Gainesville, Florida, USA.

出版信息

Ann Thorac Surg. 2011 Feb;91(2):465-71. doi: 10.1016/j.athoracsur.2010.10.005.

Abstract

BACKGROUND

We compared outcomes of arch debranching (AD) and elephant trunk (ET) techniques when used with thoracic endovascular aortic repair.

METHODS

A review was performed of consecutive patients with proximal thoracic aortic pathologies repaired with a hybrid approach.

RESULTS

Between 2005 and 2009, 58 patients underwent first-stage ET (n = 21) or AD (n = 37). Cardiopulmonary bypass was utilized in 100% of ET procedures and 68% of AD procedures (p < 0.01). Circulatory arrest was used in 86% of ET and 27% of AD cases (p < 0.01). The second stage was completed in 76% of ET and 76% of AD patients. Rates of spinal cord ischemia (ET 0 of 21, AD 0 of 37, p = 1.0), stroke (ET 2 of 21, AD 4 of 37, p = 1.0), and 30-day mortality (ET 4 of 21, AD 6 of 37, p = 1.0) were similar. Each group had one major aortic complication between the two stages. Type Ia endovascular leak at 1 and 12 months occurred in 13% ET patients and 4% AD patients at 1 month (p = 0.54) and in 0% ET patients and 4% AD patients at 12 months (p = 1.0). Kaplan-Meier estimates of survival at 1 and 12 months were 90.5% ± 6.4% and 73.1% ± 10% in the ET group, and 86.5% ± 5.6 and 71.6% ± 8.5 in the AD group, respectively (p = 0.68). The risk of a secondary procedure at 1 and 12 months was 76.2% ± 9.3% and 58.7% ± 12% in the ET group, and 71.0% ± 7.8% and 52.8% ± 10% in the AD group, respectively (p = 0.86).

CONCLUSIONS

Arch debranching achieves equivalent results to standard elephant trunk repair but with a decreased need for cardiopulmonary bypass and circulatory arrest.

摘要

背景

我们比较了在胸主动脉腔内修复术中使用主动脉弓分支去分支(AD)和象鼻技术(ET)的结果。

方法

对采用杂交技术治疗近端胸主动脉病变的连续患者进行了回顾性研究。

结果

2005 年至 2009 年间,58 例患者接受了一期 ET(n = 21)或 AD(n = 37)治疗。100%的 ET 手术和 68%的 AD 手术需要体外循环(p < 0.01)。86%的 ET 和 27%的 AD 手术使用了循环中断(p < 0.01)。第二期手术分别在 76%的 ET 和 76%的 AD 患者中完成。脊髓缺血发生率(ET 为 0/21,AD 为 0/37,p = 1.0)、中风发生率(ET 为 2/21,AD 为 4/37,p = 1.0)和 30 天死亡率(ET 为 4/21,AD 为 6/37,p = 1.0)相似。两组在两个阶段均有一个主要的主动脉并发症。一期 ET 患者有 13%和 AD 患者有 4%发生 Ia 型血管内漏,分别在 1 个月(p = 0.54)和 12 个月(p = 1.0)时发生;而 ET 患者在 12 个月时没有发生,AD 患者在 12 个月时发生 4%(p = 1.0)。ET 组的 1 个月和 12 个月的 Kaplan-Meier 生存估计分别为 90.5%±6.4%和 73.1%±10%,AD 组分别为 86.5%±5.6%和 71.6%±8.5%(p = 0.68)。ET 组 1 个月和 12 个月时再次手术的风险分别为 76.2%±9.3%和 58.7%±12%,AD 组分别为 71.0%±7.8%和 52.8%±10%(p = 0.86)。

结论

主动脉弓分支去分支与标准象鼻修复术的结果相当,但需要体外循环和循环中断的可能性更小。

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