Department of Medicine, University of Calgary, Calgary, AB, Canada.
J Gen Intern Med. 2012 Jul;27(7):878-81. doi: 10.1007/s11606-012-1996-6. Epub 2012 Jan 31.
Histamine fish poisoning, also known as scombroid poisoning, is a histamine toxicity syndrome that results from eating specific types of spoiled fish. Although typically a benign syndrome, characterized by self-limited flushing, headache, and gastrointestinal symptoms, we describe a case unique in its severity and as a precipitant of an asthma exacerbation. A 25-year-old woman presented to the emergency department (ED) with one hour of tongue and face swelling, an erythematous pruritic rash, and dyspnea with wheezing after consuming a tuna sandwich. She developed abdominal pain, diarrhea and hypotension in the ED requiring admission to the hospital. A diagnosis of histamine fish poisoning was made and the patient was treated supportively and discharged within 24 hours, but was readmitted within 3 hours due to an asthma exacerbation. Her course was complicated by recurrent admissions for asthma exacerbations.
组胺鱼类中毒，又称鲭鱼中毒，是一种由食用特定类型变质鱼引起的组胺毒性综合征。尽管通常是一种良性综合征，表现为自限性潮红、头痛和胃肠道症状，但我们描述了一个独特的严重病例，其作为哮喘恶化的诱发因素。一名 25 岁女性因食用金枪鱼三明治后 1 小时出现舌头和面部肿胀、红斑性瘙痒性皮疹和呼吸困难伴喘息而到急诊科就诊。她在急诊科出现腹痛、腹泻和低血压，需要住院治疗。诊断为组胺鱼类中毒，患者接受支持治疗并在 24 小时内出院，但在 3 小时内因哮喘恶化再次入院。她的病程复杂，反复因哮喘恶化而入院。
